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Title: Assessing endothelial function and providing calibrated UFMD data using a blood pressure cuff

Methods and apparatus are provided for assessing endothelial function in a mammal. In certain embodiments the methods involve using a cuff to apply pressure to an artery in a subject to determine a plurality of baseline values for a parameter related to endothelial function as a function of applied pressure (P.sub.m); b) applying a stimulus to the subject; and applying external pressure P.sub.m to the artery to determine a plurality of stimulus-effected values for the parameter related to endothelial function as a function of applied pressure (P.sub.m); where the baseline values are determined from measurements made when said mammal is not substantially effected by said stimulus and differences in said baseline values and said stimulus-effected values provide a measure of endothelial function in said mammal.
Inventors:
Issue Date:
OSTI Identifier:
1464470
Assignee:
The Regents of the University of California (Oakland, CA) LBNL
Patent Number(s):
10,028,664
Application Number:
15/680,082
Contract Number:
AC02-05CH11231
Resource Relation:
Patent File Date: 2017 Aug 17
Research Org:
Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States)
Sponsoring Org:
USDOE
Country of Publication:
United States
Language:
English
Subject:
59 BASIC BIOLOGICAL SCIENCES; 60 APPLIED LIFE SCIENCES

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