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Title: Assessing endothelial function and providing calibrated UFMD data using a blood pressure cuff

Methods and apparatus are provided for assessing endothelial function in a mammal. In certain embodiments the methods involve using a cuff to apply pressure to an artery in a subject to determine a plurality of baseline values for a parameter related to endothelial function as a function of applied pressure (P.sub.m); b) applying a stimulus to the subject; and applying external pressure P.sub.m to the artery to determine a plurality of stimulus-effected values for the parameter related to endothelial function as a function of applied pressure (P.sub.m); where the baseline values are determined from measurements made when said mammal is not substantially effected by said stimulus and differences in said baseline values and said stimulus-effected values provide a measure of endothelial function in said mammal.
Inventors:
Issue Date:
OSTI Identifier:
1376227
Assignee:
The Regents of the University of California LBNL
Patent Number(s):
9,737,217
Application Number:
15/236,250
Contract Number:
AC02-05CH11231
Resource Relation:
Patent File Date: 2016 Aug 12
Research Org:
Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States)
Sponsoring Org:
USDOE
Country of Publication:
United States
Language:
English
Subject:
60 APPLIED LIFE SCIENCES

Other works cited in this record:

Flow rate computer adjunct for use with an impedance plethysmograph and method
patent, November 1976

Garment for impedance plethysmograph use
patent, April 1977

Ocular plethysmograph
patent, February 1979

Eye fundus plethysmograph assembly
patent, June 1979

Impedance plethysmograph
patent, September 1979

Strain gauge plethysmograph
patent, March 1981

Digital watch/infrared plethysmograph having a removable pulse sensor unit for use with a finger cuff extension
patent, July 1981

Digital watch/infrared plethysmograph having a quick release remote pulse sensor having a finger cuff
patent, December 1981

Plethysmograph pressure correcting arrangement
patent, April 1985

Method and device for controlling the cuff pressure in measuring the blood pressure in a finger by means of photo-electric plethysmograph
patent, September 1985

Computer assisted admittance plethysmograph
patent, October 1985

Plethysmograph cuff bladder
patent, June 1986

Tourniquet for regulating applied pressures
patent, September 1991

Ultrasonic plethysmograph
patent, February 1992

Ultrasonic plethysmograph
patent, February 1993

Method of measuring blood pressure with a plethysmograph
patent, December 1993

Ultrasonic plethysmograph
patent, March 1994

Plethysmograph system and air-tight sealing assembly therefor
patent, May 1994

Whole body plethysmograph for non-invasive pulmonary measurements of unrestrained small animals
patent, January 1995

Peripheral arterial monitoring instruments
patent, May 1995

Partial body plethysmograph for measuring human respiratory system impedance
patent, May 1996

Calibration apparatus for the pressure gauges of a whole-body plethysmograph
patent, April 1997

Whole-body plethysmograph
patent, October 1997

Plethysmograph
patent, September 2000

Calibrated measurement of blood vessels and endothelium after reactive hyperemia and method therefor
patent, November 2000

Method and apparatus for noninvasive determination of peripheral arterial lumenal area
patent, October 2001

Method and system for detecting vascular conditions using an occlusive arm cuff plethysmograph
patent, January 2002

Plethysmograph pulse recognition processor
patent, October 2002

Seal for use in a volume displacement plethysmograph
patent, November 2002

Device for assessing cardiovascular function, physiological condition, and method thereof
patent, January 2003

Method and system for detecting vascular conditions using an occlusive arm cuff plethysmograph
patent, September 2003

Vascular endothelial cell function evaluating apparatus
patent, April 2004

Plethysmograph pulse recognition processor
patent, November 2004

Reduced-noise plethysmograph
patent, June 2005

Method of measuring endothelial function in a person
patent, June 2005

Method and apparatus for non-invasively evaluating endothelial activity in a patient
patent, September 2005

Plethysmograph pulse recognition processor
patent, May 2006

Method and system utilizing SpO2 plethysmograph signal to qualify NIBP pulses
patent, November 2007

Method and system of determining NIBP target inflation pressure using an SpO2 plethysmograph signal
patent, June 2008

Assessment of vascular dilatation
patent, June 2008

Adjustable table plethysmograph
patent, July 2008

Method and an apparatus for pulse plethysmograph based detection of nociception during anesthesia or sedation
patent, August 2008

Method and system utilizing SpO2 plethysmograph signal to reduce NIBP determination time
patent, December 2008

Apparatus and method of evaluating vascular endothelial function
patent, September 2014

Apparatus for evaluating vascular endothelial function
patent, October 2015

Method and system for detecting vascular conditions using an occlusive arm cuff plethysmograph
patent-application, August 2002

Superior-and -inferior-limb blood-pressure index measuring apparatus
patent-application, September 2002

Seal for Use in a Volume Displacement Plethysmograph
patent-application, September 2002

Plethysmograph pulse recognition processor
patent-application, February 2003

Reduced-noise plethysmograph
patent-application, December 2004

Assessment of vascular dilatation
patent-application, March 2005

Plethysmograph pulse recognition processor
patent-application, April 2005

Method and an apparatus for pulse plethysmograph based detection of nociception during anaesthesia or sedation
patent-application, June 2005

Method and apparatus for examining vascular endothelial functions
patent-application, October 2005

Adjustable table plethysmograph
patent-application, November 2005

Plethysmograph pulse recognition processor
patent-application, September 2006

Method and apparatus for assessing vascular endothelial function
patent-application, November 2006

Arterial endothelial function measurement method and apparatus
patent-application, November 2006

Auto-inflation cuffs
patent-application, May 2007

Large diameter plethysmograph
patent-application, August 2007

Method and Apparatus for Comprehensive Assessment of Vascular Health
patent-application, September 2007

Method and Apparatus for Determining Vascular Health Conditions
patent-application, September 2007

Wrist plethysmograph
patent-application, December 2007

Risk Assessment Method for Acute Cardiovascular Events
patent-application, January 2008

Method and System of Determining NIBP Target Inflation Pressure Using an SP02 Plethysmograph Signal
patent-application, February 2008

Methods and Apparatus for Profiling Cardiovascular Vulnerability to Mental Stress
patent-application, April 2008

Method and System Utilizing SpO2 Plethysmograph Signal to Reduce NIBP Determination Time
patent-application, April 2008

Method and Apparatus for Automated Vascular Function Testing
patent-application, May 2008

Plethysmograph Variability Processor
patent-application, August 2008

Method and Apparatus for Determining Vascular Health Conditions
patent-application, October 2008

Non-Invasive Blood Pressure Determination Method
patent-application, October 2008

Acoustic Plethysmograph for Measuring Pulmonary Function
patent-application, January 2009

Apparatus and Method of Evaluating Vascular Endothelial Function
patent-application, October 2009

Cardiovascular Health Station Methods and Apparatus
patent-application, April 2010

System and method of measuring changes in arterial volume of a limb segment
patent-application, November 2010

Method and Device for Detecting and Assessing Reactive Hyperemia Using Segmental Plethysmography
patent-application, December 2010

Apparatus for Evaluating Vascular Endothelial Function
patent-application, March 2011

Systems and Methods for Normalizing a Plethysmograph Signal for Improved Feature Analysis
patent-application, March 2011

Blood Pressure Measurement Apparatus and Blood Pressure Measurement Method
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Systems For Replicating The Beneficial Effects Of Physical Exercise And Improving Cardiovascular Health
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Radial Artery Compliance in Young, Obese, Normotensive Subjects
journal, December 1995
  • Mangoni, A. A.; Giannattasio, C.; Brunani, A.
  • Hypertension, Vol. 26, Issue 6, p. 984-988
  • DOI: 10.1161/01.HYP.26.6.984

Assessing Endothelial Vasodilator Function with the Endo-PAT 2000
journal, January 2010
  • Axtell, Andrea L.; Gomari, Fatemeh A.; Cooke, John P.
  • Journal of Visualized Experiments, Issue 44
  • DOI: 10.3791%2F2167

Non-invasive detection of endothelial dysfunction in children and adults at risk of atherosclerosis
journal, November 1992

Cross-Sectional Relations of Digital Vascular Function to Cardiovascular Risk Factors in the Framingham Heart Study
journal, May 2008

Assessment of Endothelial Function in the Radial Artery Using Inhaled Albuterol
conference, August 2007

Role of nitric oxide in the regulation of digital pulse volume amplitude in humans
journal, August 2006

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