DOE Patents title logo U.S. Department of Energy
Office of Scientific and Technical Information

Title: Assessing endothelial function and providing calibrated UFMD data using a blood pressure cuff

Abstract

Methods and apparatus are provided for assessing endothelial function in a mammal. In certain embodiments the methods involve using a cuff to apply pressure to an artery in a subject to determine a plurality of baseline values for a parameter related to endothelial function as a function of applied pressure (Pm); b) applying a stimulus to the subject; and applying external pressure Pm to the artery to determine a plurality of stimulus-effected values for the parameter related to endothelial function as a function of applied pressure (Pm); where the baseline values are determined from measurements made when said mammal is not substantially effected by said stimulus and differences in said baseline values and said stimulus-effected values provide a measure of endothelial function in said mammal.

Inventors:
Issue Date:
Research Org.:
Lawrence Berkeley National Laboratory (LBNL), Berkeley, CA (United States)
Sponsoring Org.:
USDOE
OSTI Identifier:
1568354
Patent Number(s):
10292597
Application Number:
16/042,936
Assignee:
The Regents of the University of California (Oakland, CA)
Patent Classifications (CPCs):
A - HUMAN NECESSITIES A61 - MEDICAL OR VETERINARY SCIENCE A61B - DIAGNOSIS
G - PHYSICS G16 - INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS G16H - HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
DOE Contract Number:  
AC02-05CH11231
Resource Type:
Patent
Resource Relation:
Patent File Date: 07/23/2018
Country of Publication:
United States
Language:
English
Subject:
59 BASIC BIOLOGICAL SCIENCES

Citation Formats

Maltz, Jonathan S. Assessing endothelial function and providing calibrated UFMD data using a blood pressure cuff. United States: N. p., 2019. Web.
Maltz, Jonathan S. Assessing endothelial function and providing calibrated UFMD data using a blood pressure cuff. United States.
Maltz, Jonathan S. Tue . "Assessing endothelial function and providing calibrated UFMD data using a blood pressure cuff". United States. https://www.osti.gov/servlets/purl/1568354.
@article{osti_1568354,
title = {Assessing endothelial function and providing calibrated UFMD data using a blood pressure cuff},
author = {Maltz, Jonathan S.},
abstractNote = {Methods and apparatus are provided for assessing endothelial function in a mammal. In certain embodiments the methods involve using a cuff to apply pressure to an artery in a subject to determine a plurality of baseline values for a parameter related to endothelial function as a function of applied pressure (Pm); b) applying a stimulus to the subject; and applying external pressure Pm to the artery to determine a plurality of stimulus-effected values for the parameter related to endothelial function as a function of applied pressure (Pm); where the baseline values are determined from measurements made when said mammal is not substantially effected by said stimulus and differences in said baseline values and said stimulus-effected values provide a measure of endothelial function in said mammal.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {2019},
month = {5}
}

Works referenced in this record:

Apparatus for evaluating vascular endothelial function
patent, October 2015


Method and apparatus for examining vascular endothelial functions
patent-application, October 2005


Seal for Use in a Volume Displacement Plethysmograph
patent-application, September 2002


Calibrated measurement of blood vessels and endothelium after reactive hyperemia and method therefor
patent-application, April 2003


Plethysmograph Variability Processor
patent-application, August 2008


Method and apparatus for non-invasively evaluating endothelial activity in a patient
patent, September 2005


Systems and Methods for Normalizing a Plethysmograph Signal for Improved Feature Analysis
patent-application, March 2011


Ocular plethysmograph
patent, February 1979


Method and system utilizing SpO2 plethysmograph signal to qualify NIBP pulses
patent, November 2007


Non-Invasive Blood Pressure Determination Method
patent-application, October 2008


Impedance plethysmograph
patent, September 1979


Reduced-noise plethysmograph
patent, June 2005


Apparatus and Method of Evaluating Vascular Endothelial Function
patent-application, October 2009


Method of measuring endothelial function in a person
patent, June 2005


Ultrasonic plethysmograph
patent, March 1994


Plethysmograph cuff bladder
patent, June 1986


Tourniquet for regulating applied pressures
patent, September 1991


Method and Apparatus for Determining Vascular Health Conditions
patent-application, September 2007


Apparatus for Evaluating Vascular Endothelial Function
patent-application, March 2011


Apparatus and method for vascular examination of a limb
patent, February 1992


System and method of measuring changes in arterial volume of a limb segment
patent-application, November 2010


Assessing Endothelial Function Using a Blood Pressure Cuff
patent-application, May 2014


Strain gauge plethysmograph
patent, March 1981


Ultrasonic plethysmograph
patent, February 1993


Adjustable table plethysmograph
patent-application, November 2005


Plethysmograph pulse recognition processor
patent, October 2002


Method and Apparatus for Determining Vascular Health Conditions
patent-application, October 2008


Whole-body plethysmograph
patent, October 1997


Plethysmograph pulse recognition processor
patent, November 2004


Plethysmograph system and air-tight sealing assembly therefor
patent, May 1994


Assessing Endothelial Function Using a Blood Pressure Cuff
patent-application, December 2015


Method and apparatus for noninvasive determination of peripheral arterial lumenal area
patent, October 2001


Large diameter plethysmograph
patent-application, August 2007


Assessment of vascular dilatation
patent-application, March 2005


Method and Apparatus for Automated Vascular Function Testing
patent-application, May 2008


Reduced-noise plethysmograph
patent-application, December 2004


Plethysmograph pulse recognition processor
patent-application, February 2003


Method and System of Determining NIBP Target Inflation Pressure Using an SP02 Plethysmograph Signal
patent-application, February 2008


Plethysmograph pulse recognition processor
patent-application, April 2005


Method and Apparatus for Comprehensive Assessment of Vascular Health
patent-application, September 2007


Apparatus and method of evaluating vascular endothelial function
patent, September 2014


Cardiovascular Health Station Methods and Apparatus
patent-application, April 2010


Apparatus for evaluating vascular endothelial function
patent, September 2016


Method and an apparatus for pulse plethysmograph based detection of nociception during anaesthesia or sedation
patent-application, June 2005


Arterial endothelial function measurement method and apparatus
patent-application, November 2006


Plethysmograph
patent, September 2000


Method and system for detecting vascular conditions using an occlusive arm cuff plethysmograph
patent-application, August 2002


Adjustable table plethysmograph
patent, July 2008


Method and System Utilizing SpO2 Plethysmograph Signal to Reduce NIBP Determination Time
patent-application, April 2008


Method of measuring blood pressure with a plethysmograph
patent, December 1993


Auto-inflation cuffs
patent-application, May 2007


Risk Assessment Method for Acute Cardiovascular Events
patent-application, January 2008


Method and system utilizing SpO2 plethysmograph signal to reduce NIBP determination time
patent, December 2008


Adaptive pneumatic tourniquet
patent, October 1984


Blood Pressure Measurement Apparatus and Blood Pressure Measurement Method
patent-application, June 2013


Ultrasonic plethysmograph
patent, February 1992


Systems For Replicating The Beneficial Effects Of Physical Exercise And Improving Cardiovascular Health
patent-application, April 2014


Method and Device for Detecting and Assessing Reactive Hyperemia Using Segmental Plethysmography
patent-application, December 2010


Wrist plethysmograph
patent-application, December 2007


Methods and Apparatus for Profiling Cardiovascular Vulnerability to Mental Stress
patent-application, April 2008


Superior-and -inferior-limb blood-pressure index measuring apparatus
patent-application, September 2002


Method and Device for Detecting and Assessing Reactive Hyperemia Using Segmental Plethysmography
patent-application, September 2014


Method and apparatus for assessing vascular endothelial function
patent-application, November 2006


Acoustic Plethysmograph for Measuring Pulmonary Function
patent-application, January 2009


Vascular endothelial cell function evaluating apparatus
patent, April 2004


Plethysmograph pulse recognition processor
patent-application, September 2006