Assessing endothelial function and providing calibrated UFMD data using a blood pressure cuff

Maltz, Jonathan S.

Title: Assessing endothelial function and providing calibrated UFMD data using a blood pressure cuff

Patent · Tue Aug 22 00:00:00 EDT 2017

OSTI ID:1376227

Maltz, Jonathan S.

Methods and apparatus are provided for assessing endothelial function in a mammal. In certain embodiments the methods involve using a cuff to apply pressure to an artery in a subject to determine a plurality of baseline values for a parameter related to endothelial function as a function of applied pressure (P.sub.m); b) applying a stimulus to the subject; and applying external pressure P.sub.m to the artery to determine a plurality of stimulus-effected values for the parameter related to endothelial function as a function of applied pressure (P.sub.m); where the baseline values are determined from measurements made when said mammal is not substantially effected by said stimulus and differences in said baseline values and said stimulus-effected values provide a measure of endothelial function in said mammal.

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Research Organization:: Lawrence Berkeley National Laboratory (LBNL), Berkeley, CA (United States)

Sponsoring Organization:: USDOE

DOE Contract Number:: AC02-05CH11231

Assignee:: The Regents of the University of California

Patent Number(s):: 9,737,217

Application Number:: 15/236,250

OSTI ID:: 1376227

Resource Relation:: Patent File Date: 2016 Aug 12

Country of Publication:: United States

Language:: English

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