Methods for chromosome-specific staining
Abstract
Methods and compositions for chromosome-specific staining are provided. Compositions comprise heterogenous mixtures of labeled nucleic acid fragments having substantially complementary base sequences to unique sequence regions of the chromosomal DNA for which their associated staining reagent is specific. Methods include methods for making the chromosome-specific staining compositions of the invention, and methods for applying the staining compositions to chromosomes.
- Inventors:
-
- Livermore, CA
- Walnut Creek, CA
- Issue Date:
- Research Org.:
- Lawrence Livermore National Laboratory (LLNL), Livermore, CA (United States)
- OSTI Identifier:
- 870054
- Patent Number(s):
- 5447841
- Assignee:
- Regents Of Univ. Of California (Oakland, CA)
- Patent Classifications (CPCs):
-
C - CHEMISTRY C12 - BIOCHEMISTRY C12Q - MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS
Y - NEW / CROSS SECTIONAL TECHNOLOGIES Y10 - TECHNICAL SUBJECTS COVERED BY FORMER USPC Y10S - TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- DOE Contract Number:
- W-7405-ENG-48
- Resource Type:
- Patent
- Country of Publication:
- United States
- Language:
- English
- Subject:
- methods; chromosome-specific; staining; compositions; provided; comprise; heterogenous; mixtures; labeled; nucleic; acid; fragments; substantially; complementary; base; sequences; unique; sequence; regions; chromosomal; dna; associated; reagent; specific; applying; chromosomes; compositions comprise; base sequences; chromosomal dna; nucleic acid; base sequence; chromosome-specific staining; complementary base; substantially complementary; staining reagent; acid fragment; /435/436/999/
Citation Formats
Gray, Joe W, and Pinkel, Daniel. Methods for chromosome-specific staining. United States: N. p., 1995.
Web.
Gray, Joe W, & Pinkel, Daniel. Methods for chromosome-specific staining. United States.
Gray, Joe W, and Pinkel, Daniel. Sun .
"Methods for chromosome-specific staining". United States. https://www.osti.gov/servlets/purl/870054.
@article{osti_870054,
title = {Methods for chromosome-specific staining},
author = {Gray, Joe W and Pinkel, Daniel},
abstractNote = {Methods and compositions for chromosome-specific staining are provided. Compositions comprise heterogenous mixtures of labeled nucleic acid fragments having substantially complementary base sequences to unique sequence regions of the chromosomal DNA for which their associated staining reagent is specific. Methods include methods for making the chromosome-specific staining compositions of the invention, and methods for applying the staining compositions to chromosomes.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {Sun Jan 01 00:00:00 EST 1995},
month = {Sun Jan 01 00:00:00 EST 1995}
}
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