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Title: Antibody evolution immunogens

Abstract

The present invention relates, in general, to HIV-1 and, in particular, to broadly neutralizing HIV-1 antibodies, and to HIV-1 immunogens and to methods of using such immunogens to induce the production of broadly neutralizing HIV-1 antibodies in a subject (e.g., a human).

Inventors:
; ; ; ; ; ; ; ; ; ; ;
Issue Date:
Research Org.:
Los Alamos National Lab. (LANL), Los Alamos, NM (United States)
Sponsoring Org.:
USDOE
OSTI Identifier:
1771680
Patent Number(s):
10849970
Application Number:
15/864,822
Assignee:
Duke University (Durham, NC); Triad National Security, LLC (Los Alamos, NM); The Trustees of the University of Pennsylvania (Philadelphia, PA); TRUSTEES OF BOSTON UNIVERSITY (Boston, MA); The United States of America, as represented by the Secretary, Department of Health and Human Services (Rockville, MD); The Board of Trustees of the Leland Stanford Junior University (Palo Alto, CA)
Patent Classifications (CPCs):
C - CHEMISTRY C07 - ORGANIC CHEMISTRY C07K - PEPTIDES
C - CHEMISTRY C12 - BIOCHEMISTRY C12N - MICROORGANISMS OR ENZYMES
DOE Contract Number:  
AC52-06NA25396
Resource Type:
Patent
Resource Relation:
Patent File Date: 01/08/2018
Country of Publication:
United States
Language:
English

Citation Formats

Haynes, Barton F., Liao, Hua-Xin, Lynch, Rebecca M., Zhou, Tongqing, Gao, Feng, Boyd, Scott, Shaw, George M., Hahn, Beatrice H., Kepler, Thomas B., Korber, Bette T., Kwong, Peter, and Mascola, John R. Antibody evolution immunogens. United States: N. p., 2020. Web.
Haynes, Barton F., Liao, Hua-Xin, Lynch, Rebecca M., Zhou, Tongqing, Gao, Feng, Boyd, Scott, Shaw, George M., Hahn, Beatrice H., Kepler, Thomas B., Korber, Bette T., Kwong, Peter, & Mascola, John R. Antibody evolution immunogens. United States.
Haynes, Barton F., Liao, Hua-Xin, Lynch, Rebecca M., Zhou, Tongqing, Gao, Feng, Boyd, Scott, Shaw, George M., Hahn, Beatrice H., Kepler, Thomas B., Korber, Bette T., Kwong, Peter, and Mascola, John R. Tue . "Antibody evolution immunogens". United States. https://www.osti.gov/servlets/purl/1771680.
@article{osti_1771680,
title = {Antibody evolution immunogens},
author = {Haynes, Barton F. and Liao, Hua-Xin and Lynch, Rebecca M. and Zhou, Tongqing and Gao, Feng and Boyd, Scott and Shaw, George M. and Hahn, Beatrice H. and Kepler, Thomas B. and Korber, Bette T. and Kwong, Peter and Mascola, John R.},
abstractNote = {The present invention relates, in general, to HIV-1 and, in particular, to broadly neutralizing HIV-1 antibodies, and to HIV-1 immunogens and to methods of using such immunogens to induce the production of broadly neutralizing HIV-1 antibodies in a subject (e.g., a human).},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {2020},
month = {12}
}

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