Immunogenic peptides comprising a T-helper epitope and a B-cell neutralizing antibody epitope
Abstract
The present invention relates, generally, to a polyvalent immunogen and, more particularly, to a method of inducing neutralizing antibodies against HIV and to a polyvalent immunogen suitable for use in such a method.
- Inventors:
-
- Durham, NC
- Los Alamos, NM
- Issue Date:
- Research Org.:
- Univ. of California (United States); Los Alamos National Laboratory (LANL), Los Alamos, NM (United States)
- Sponsoring Org.:
- USDOE
- OSTI Identifier:
- 904221
- Patent Number(s):
- 7153509
- Application Number:
- 10/289,228
- Assignee:
- Duke University (Durham, NC); The Regents of the University of Calforinia (Oakland, CA)
- Patent Classifications (CPCs):
-
A - HUMAN NECESSITIES A61 - MEDICAL OR VETERINARY SCIENCE A61K - PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
A - HUMAN NECESSITIES A61 - MEDICAL OR VETERINARY SCIENCE A61P - SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- DOE Contract Number:
- W-7405-ENG-36
- Resource Type:
- Patent
- Country of Publication:
- United States
- Language:
- English
- Subject:
- 59 BASIC BIOLOGICAL SCIENCES
Citation Formats
Haynes, Barton F, Korber, Bette T, and De Lorimier, Robert M. Immunogenic peptides comprising a T-helper epitope and a B-cell neutralizing antibody epitope. United States: N. p., 2006.
Web.
Haynes, Barton F, Korber, Bette T, & De Lorimier, Robert M. Immunogenic peptides comprising a T-helper epitope and a B-cell neutralizing antibody epitope. United States.
Haynes, Barton F, Korber, Bette T, and De Lorimier, Robert M. Tue .
"Immunogenic peptides comprising a T-helper epitope and a B-cell neutralizing antibody epitope". United States. https://www.osti.gov/servlets/purl/904221.
@article{osti_904221,
title = {Immunogenic peptides comprising a T-helper epitope and a B-cell neutralizing antibody epitope},
author = {Haynes, Barton F and Korber, Bette T and De Lorimier, Robert M},
abstractNote = {The present invention relates, generally, to a polyvalent immunogen and, more particularly, to a method of inducing neutralizing antibodies against HIV and to a polyvalent immunogen suitable for use in such a method.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {Tue Dec 26 00:00:00 EST 2006},
month = {Tue Dec 26 00:00:00 EST 2006}
}
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Works referenced in this record:
Safety and immunogenicity of an HLA-based HIV envelope polyvalent synthetic peptide immunogen
journal, January 1998
- Bartlett, John A.; Wasserman, Steven S.; Hicks, Charles B.
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HIV Vaccine Development at Duke University Medical Center
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- Haynes, Barton F.; Liao, Hua-Xin; Staats, Herman F.
- Immunologic Research, Vol. 22, Issue 2-3
HIV Type 1 V3 Region Primer-Induced Antibody Suppression Is Overcome by Administration of C4-V3 Peptides as a Polyvalent Immunogen
journal, February 1995
- Haynes, Barton F.; Moody, M. Anthony; Heinley, Craig S.
- AIDS Research and Human Retroviruses, Vol. 11, Issue 2
Phage display of peptide epitopes from HIV-1 elicits strong cytolytic responses
journal, August 2000
- De Berardinis, Piergiuseppe; Sartorius, Rossella; Fanutti, Cristina
- Nature Biotechnology, Vol. 18, Issue 8