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Title: Mosaic clade M human immunodeficiency virus type 1 (HIV-1) envelope immunogens

Abstract

The present invention relates to mosaic clade M HIV-1 Env polypeptides and to compositions comprising same. The polypeptides of the invention are suitable for use in inducing an immune response to HIV-1 in a human.

Inventors:
 [1];  [1];  [2];  [2];  [3];  [4]
  1. Los Alamos, NM
  2. Durham, NC
  3. Boston, MA
  4. Birmingham, AL
Issue Date:
Research Org.:
Los Alamos National Lab. (LANL), Los Alamos, NM (United States)
Sponsoring Org.:
USDOE
OSTI Identifier:
1019397
Patent Number(s):
7951377
Application Number:
12/192,015
Assignee:
Los Alamos National Security, LLC (Los Alamos, NM); Duke University (Durham, NC); Beth Isreal Deaconess Medical Center (Boston, MA); The University of Albama at Birmingham Research Foundation (Birmingham, AL)
Patent Classifications (CPCs):
C - CHEMISTRY C07 - ORGANIC CHEMISTRY C07K - PEPTIDES
C - CHEMISTRY C12 - BIOCHEMISTRY C12N - MICROORGANISMS OR ENZYMES
DOE Contract Number:  
AC52-06NA25396
Resource Type:
Patent
Country of Publication:
United States
Language:
English
Subject:
60 APPLIED LIFE SCIENCES

Citation Formats

Korber, Bette T., Fischer, William, Liao, Hua-Xin, Haynes, Barton F., Letvin, Norman, and Hahn, Beatrice H. Mosaic clade M human immunodeficiency virus type 1 (HIV-1) envelope immunogens. United States: N. p., 2011. Web.
Korber, Bette T., Fischer, William, Liao, Hua-Xin, Haynes, Barton F., Letvin, Norman, & Hahn, Beatrice H. Mosaic clade M human immunodeficiency virus type 1 (HIV-1) envelope immunogens. United States.
Korber, Bette T., Fischer, William, Liao, Hua-Xin, Haynes, Barton F., Letvin, Norman, and Hahn, Beatrice H. Tue . "Mosaic clade M human immunodeficiency virus type 1 (HIV-1) envelope immunogens". United States. https://www.osti.gov/servlets/purl/1019397.
@article{osti_1019397,
title = {Mosaic clade M human immunodeficiency virus type 1 (HIV-1) envelope immunogens},
author = {Korber, Bette T. and Fischer, William and Liao, Hua-Xin and Haynes, Barton F. and Letvin, Norman and Hahn, Beatrice H.},
abstractNote = {The present invention relates to mosaic clade M HIV-1 Env polypeptides and to compositions comprising same. The polypeptides of the invention are suitable for use in inducing an immune response to HIV-1 in a human.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {2011},
month = {5}
}

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Works referenced in this record:

Polygene DNA vaccine induces a high level of protective effect against HIV-vaccinia virus challenge in mice
journal, September 2004