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Title: Tritioacetylating reagents and processes for preparation thereof

Abstract

Novel acetylating and tritioacetylating reagents suitable for preparation of nonlabelled and radiolabelled organic compounds. N-acetoxynaphthalimide, N-tritioacetoxyphthalimide, N-tritioacetoxysuccinimide, N-tritioacetoxynaphthalimide and processes of their preparation. The invention also concerns synthesis of nonlabelled acetylated and tritioacetylated organic compounds from precursors containing a free --NH.sub.2, --SH or --OH group.

Inventors:
 [1];  [2];  [3];  [4]
  1. Moraga, CA
  2. El Cerrito, CA
  3. Oakland, CA
  4. Lafayette, CA
Issue Date:
Research Org.:
Lawrence Berkeley National Laboratory (LBNL), Berkeley, CA (United States)
OSTI Identifier:
873442
Patent Number(s):
6160128
Assignee:
Regents of University of California (Oakland, CA)
Patent Classifications (CPCs):
C - CHEMISTRY C07 - ORGANIC CHEMISTRY C07D - HETEROCYCLIC COMPOUNDS
DOE Contract Number:  
AC03-76SF00098
Resource Type:
Patent
Country of Publication:
United States
Language:
English
Subject:
tritioacetylating; reagents; processes; preparation; novel; acetylating; suitable; nonlabelled; radiolabelled; organic; compounds; n-acetoxynaphthalimide; n-tritioacetoxyphthalimide; n-tritioacetoxysuccinimide; n-tritioacetoxynaphthalimide; concerns; synthesis; acetylated; tritioacetylated; precursors; containing; free; -nh; -sh; -oh; organic compound; organic compounds; reagents suitable; tritioacetylating reagents; /999/

Citation Formats

Saljoughian, Manoucher, Morimoto, Hiromi, Williams, Philip G, and Than, Chit. Tritioacetylating reagents and processes for preparation thereof. United States: N. p., 2000. Web.
Saljoughian, Manoucher, Morimoto, Hiromi, Williams, Philip G, & Than, Chit. Tritioacetylating reagents and processes for preparation thereof. United States.
Saljoughian, Manoucher, Morimoto, Hiromi, Williams, Philip G, and Than, Chit. Sat . "Tritioacetylating reagents and processes for preparation thereof". United States. https://www.osti.gov/servlets/purl/873442.
@article{osti_873442,
title = {Tritioacetylating reagents and processes for preparation thereof},
author = {Saljoughian, Manoucher and Morimoto, Hiromi and Williams, Philip G and Than, Chit},
abstractNote = {Novel acetylating and tritioacetylating reagents suitable for preparation of nonlabelled and radiolabelled organic compounds. N-acetoxynaphthalimide, N-tritioacetoxyphthalimide, N-tritioacetoxysuccinimide, N-tritioacetoxynaphthalimide and processes of their preparation. The invention also concerns synthesis of nonlabelled acetylated and tritioacetylated organic compounds from precursors containing a free --NH.sub.2, --SH or --OH group.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {Sat Jan 01 00:00:00 EST 2000},
month = {Sat Jan 01 00:00:00 EST 2000}
}

Works referenced in this record:

N -Tritioacetoxyphthalimide:  A New High Specific Activity Tritioacetylating Reagent
journal, January 1996


The synthesis of N-[3H] acetyl muramyl dipeptides of high specific radioactivity
journal, June 1983


Evidence for species-specific substrate-site-directed inactivation of rabbit adenylate kinase by N6-(6-iodoacetamido-n-hexyl)adenosine 5'-triphosphate
journal, November 1976


The acetylation of insulin
journal, March 1971


Preparation, NMR Characterization, and Labeling Reactions of Tritiated Borane-THF Complex at High Specific Radioactivity
journal, November 1995


A New Method for the Preparation of N -Acyloxyphthalimides and N -Acyloxysuccinimides
journal, January 1977


The synthesis of N-acetylphenylalanyl-sRNA
journal, October 1966