Gel-forming reagents and uses thereof for preparing microarrays
Abstract
New gel-forming reagents including monomers and cross-linkers, which can be applied to gel-drop microarray manufacturing by using co-polymerization approaches are disclosed. Compositions for the preparation of co-polymerization mixtures with new gel-forming monomers and cross-linker reagents are described herein. New co-polymerization compositions and cross-linkers with variable length linker groups between unsaturated C.dbd.C bonds that participate in the formation of gel networks are disclosed.
- Inventors:
-
- Burr Ridge, IL
- Woodridge, IL
- Issue Date:
- Research Org.:
- Argonne National Laboratory (ANL), Argonne, IL (United States)
- Sponsoring Org.:
- USDOE
- OSTI Identifier:
- 1014932
- Patent Number(s):
- 7829644
- Application Number:
- US Patent Application 11/550,730
- Assignee:
- UChicago Argonne, LLC (Chicago, IL)
- Patent Classifications (CPCs):
-
C - CHEMISTRY C08 - ORGANIC MACROMOLECULAR COMPOUNDS C08F - MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
- DOE Contract Number:
- AC02-06CH11357
- Resource Type:
- Patent
- Country of Publication:
- United States
- Language:
- English
Citation Formats
Golova, Julia, Chernov, Boris, and Perov, Alexander. Gel-forming reagents and uses thereof for preparing microarrays. United States: N. p., 2010.
Web.
Golova, Julia, Chernov, Boris, & Perov, Alexander. Gel-forming reagents and uses thereof for preparing microarrays. United States.
Golova, Julia, Chernov, Boris, and Perov, Alexander. Tue .
"Gel-forming reagents and uses thereof for preparing microarrays". United States. https://www.osti.gov/servlets/purl/1014932.
@article{osti_1014932,
title = {Gel-forming reagents and uses thereof for preparing microarrays},
author = {Golova, Julia and Chernov, Boris and Perov, Alexander},
abstractNote = {New gel-forming reagents including monomers and cross-linkers, which can be applied to gel-drop microarray manufacturing by using co-polymerization approaches are disclosed. Compositions for the preparation of co-polymerization mixtures with new gel-forming monomers and cross-linker reagents are described herein. New co-polymerization compositions and cross-linkers with variable length linker groups between unsaturated C.dbd.C bonds that participate in the formation of gel networks are disclosed.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {Tue Nov 09 00:00:00 EST 2010},
month = {Tue Nov 09 00:00:00 EST 2010}
}
Works referenced in this record:
Hydrazide oligonucleotides: new chemical modification for chip array attachment and conjugation
journal, November 2002
- Raddatz, S.
- Nucleic Acids Research, Vol. 30, Issue 21
DNA analysis and diagnostics on oligonucleotide microchips.
journal, May 1996
- Yershov, G.; Barsky, V.; Belgovskiy, A.
- Proceedings of the National Academy of Sciences, Vol. 93, Issue 10
Strategies in the Preparation of DNA Oligonucleotide Arrays for Diagnostic Applications
journal, August 2001
- Beaucage, Serge
- Current Medicinal Chemistry, Vol. 8, Issue 10
Hydrogel-Based Protein Microchips: Manufacturing, Properties, and Applications
journal, May 2003
- Rubina, A. Yu.; Dementieva, E. I.; Stomakhin, A. A.
- BioTechniques, Vol. 34, Issue 5
DNA microarrays with stem–loop DNA probes: preparation and applications
journal, October 2001
- Broude, Natalia E.; Woodward, Karen; Cavallo, Robert
- Nucleic Acids Research, Vol. 29, Issue 19
Hydrogel drop microchips with immobilized DNA: properties and methods for large-scale production
journal, February 2004
- Rubina, A. Yu; Pan’kov, S. V.; Dementieva, E. I.
- Analytical Biochemistry, Vol. 325, Issue 1
A Rapid Method for the Construction of Oligonucleotide Arrays
journal, May 2003
- Kumar, P.; Gupta, K. C.
- Bioconjugate Chemistry, Vol. 14, Issue 3
DNA biochip arraying, detection and amplification strategies
journal, January 2004
- Campàs, M.; Katakis, I.
- TrAC Trends in Analytical Chemistry, Vol. 23, Issue 1
Immobilization of Oligonucleotides onto a Glass Support via Disulfide Bonds: A Method for Preparation of DNA Microarrays
journal, January 1999
- Rogers, Yu-Hui; Jiang-Baucom, Ping; Huang, Zhi-Jian
- Analytical Biochemistry, Vol. 266, Issue 1
Site-Specific Protein Immobilization by Staudinger Ligation
journal, October 2003
- Soellner, Matthew B.; Dickson, Kimberly A.; Nilsson, Bradley L.
- Journal of the American Chemical Society, Vol. 125, Issue 39
Design of Oligonucleotide Arrays at Interfaces
journal, June 1999
- Boncheva, Mila; Scheibler, Lukas; Lincoln, Per
- Langmuir, Vol. 15, Issue 13
Functional protein microarrays: ripe for discovery
journal, February 2004
- Predki, Paul F.
- Current Opinion in Chemical Biology, Vol. 8, Issue 1
Protein microarrays: challenges and promises
journal, July 2002
- Talapatra, Anupam; Rouse, Richard; Hardiman, Gary
- Pharmacogenomics, Vol. 3, Issue 4
Arrays in biological and chemical analysis
journal, February 2002
- Christensen, C.
- Talanta, Vol. 56, Issue 2
Direct fluorescence analysis of genetic polymorphisms by hybridization with oligonucleotide arrays on glass supports
journal, January 1994
- Guo, Zhen; Guilfoyle, Richard A.; Thiel, Andrew J.
- Nucleic Acids Research, Vol. 22, Issue 24
Immobilization of acrylamide-modified oligonucleotides by co-polymerization
journal, January 1999
- Rehman, F. N.; Audeh, M.; Abrams, E. S.
- Nucleic Acids Research, Vol. 27, Issue 2
Covalent attachment of synthetic DNA to self-assembled monolayer films
journal, August 1996
- Chrisey, L.
- Nucleic Acids Research, Vol. 24, Issue 15
Fabrication of Microarray of Gel-Immobilized Compounds on a Chip by Copolymerization
journal, September 1999
- Vasiliskov, A. V.; Timofeev, E. N.; Surzhikov, S. A.
- BioTechniques, Vol. 27, Issue 3
Semicarbazide-Functionalized Si(111) Surfaces for the Site-Specific Immobilization of Peptides
journal, February 2005
- Coffinier, Y.; Olivier, C.; Perzyna, A.
- Langmuir, Vol. 21, Issue 4
Covalent Attachment of Hybridizable Oligonucleotides to Glass Supports
journal, April 1997
- Joos, Beda; Kuster, Herbert; Cone, Richard
- Analytical Biochemistry, Vol. 247, Issue 1
Diels−Alder Reaction for the Selective Immobilization of Protein to Electroactive Self-Assembled Monolayers
journal, May 1999
- Yousaf, Muhammad N.; Mrksich, Milan
- Journal of the American Chemical Society, Vol. 121, Issue 17
Carbohydrate Arrays for the Evaluation of Protein Binding and Enzymatic Modification
journal, April 2002
- Houseman, Benjamin T.; Mrksich, Milan
- Chemistry & Biology, Vol. 9, Issue 4
Fabrication and Surface Characterization of DNA Microarrays Using Amine- and Thiol-Terminated Oligonucleotide Probes †
journal, March 2003
- Charles, Paul T.; Vora, Gary J.; Andreadis, Joanne D.
- Langmuir, Vol. 19, Issue 5
Radical-generating coordination complexes as tools for rapid and effective fragmentation and fluorescent labeling of nucleic acids for microchip hybridization
journal, December 2002
- Kelly, John J.; Chernov, Boris K.; Tovstanovsky, Igor
- Analytical Biochemistry, Vol. 311, Issue 2
DNA microarrays: raising the profile
journal, February 2001
- van Berkum, Nynke L.; Holstege, Frank CP
- Current Opinion in Biotechnology, Vol. 12, Issue 1