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Title: Process for the preparation of protected dihydroxypropyl trialkylammonium salts and derivatives thereof

Abstract

A process for the preparation of protected dihydroxypropyl trialkylammonium salts, particularly in chiral form is described. In particular, a process for the preparation of (2,2-dimethyl-1,3-dioxolan-4-ylmethyl)trialkylammonium salts, particularly in chiral form is described. Furthermore, a process is described wherein the (2,2-dimethyl-1,3-dioxolan-4ylmethyl)trialkylammonium salts is a 2,2-dimethyl-1,3-dioxolan-4-ylmethyl trimethylammonium salt, preferably in chiral form. The protected dihydroxypropyl trialkylammonium salts lead to L-carnitine (9) when in chiral form (5).

Inventors:
 [1];  [2]
  1. Haslett, MI
  2. East Lansing, MI
Issue Date:
Research Org.:
Michigan State Univ., East Lansing, MI (United States)
OSTI Identifier:
873072
Patent Number(s):
6084131
Assignee:
Board of Trustees operating Michigan State University (East Lansing, MI)
Patent Classifications (CPCs):
C - CHEMISTRY C07 - ORGANIC CHEMISTRY C07D - HETEROCYCLIC COMPOUNDS
C - CHEMISTRY C07 - ORGANIC CHEMISTRY C07C - ACYCLIC OR CARBOCYCLIC COMPOUNDS
DOE Contract Number:  
FG02-89ER14029
Resource Type:
Patent
Country of Publication:
United States
Language:
English
Subject:
process; preparation; protected; dihydroxypropyl; trialkylammonium; salts; derivatives; particularly; chiral; form; described; particular; 2-dimethyl-1; 3-dioxolan-4-ylmethyl; furthermore; 3-dioxolan-4ylmethyl; trimethylammonium; salt; preferably; lead; l-carnitine; trialkylammonium salts; protected dihydroxypropyl; ammonium salts; ammonium salt; chiral form; dihydroxypropyl trialkylammonium; /999/

Citation Formats

Hollingsworth, Rawle I, and Wang, Guijun. Process for the preparation of protected dihydroxypropyl trialkylammonium salts and derivatives thereof. United States: N. p., 2000. Web.
Hollingsworth, Rawle I, & Wang, Guijun. Process for the preparation of protected dihydroxypropyl trialkylammonium salts and derivatives thereof. United States.
Hollingsworth, Rawle I, and Wang, Guijun. Sat . "Process for the preparation of protected dihydroxypropyl trialkylammonium salts and derivatives thereof". United States. https://www.osti.gov/servlets/purl/873072.
@article{osti_873072,
title = {Process for the preparation of protected dihydroxypropyl trialkylammonium salts and derivatives thereof},
author = {Hollingsworth, Rawle I and Wang, Guijun},
abstractNote = {A process for the preparation of protected dihydroxypropyl trialkylammonium salts, particularly in chiral form is described. In particular, a process for the preparation of (2,2-dimethyl-1,3-dioxolan-4-ylmethyl)trialkylammonium salts, particularly in chiral form is described. Furthermore, a process is described wherein the (2,2-dimethyl-1,3-dioxolan-4ylmethyl)trialkylammonium salts is a 2,2-dimethyl-1,3-dioxolan-4-ylmethyl trimethylammonium salt, preferably in chiral form. The protected dihydroxypropyl trialkylammonium salts lead to L-carnitine (9) when in chiral form (5).},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {2000},
month = {1}
}

Patent:

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