Conjugate and method for forming aminomethyl phosphorus conjugates
Abstract
A method of forming phosphine-amine conjugates includes reacting a hydroxymethyl phosphine group of an amine-free first molecule with at least one free amine group of a second molecule to covalently bond the first molecule with the second molecule through an aminomethyl phosphorus linkage and the conjugates formed thereby.
- Inventors:
-
- Columbia, MO
- Issue Date:
- Research Org.:
- Univ. of Missouri, Columbia, MO (United States)
- OSTI Identifier:
- 872500
- Patent Number(s):
- 5948386
- Assignee:
- Curators of University of Missouri (Columbia, MO)
- Patent Classifications (CPCs):
-
A - HUMAN NECESSITIES A61 - MEDICAL OR VETERINARY SCIENCE A61K - PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
- DOE Contract Number:
- FG02-89ER60875
- Resource Type:
- Patent
- Country of Publication:
- United States
- Language:
- English
- Subject:
- conjugate; method; forming; aminomethyl; phosphorus; conjugates; phosphine-amine; reacting; hydroxymethyl; phosphine; amine-free; molecule; free; amine; covalently; bond; linkage; formed; hydroxymethyl phosphine; /424/999/
Citation Formats
Katti, Kattesh V, Berning, Douglas E, Volkert, Wynn A, Ketring, Alan R, and Churchill, Robert. Conjugate and method for forming aminomethyl phosphorus conjugates. United States: N. p., 1999.
Web.
Katti, Kattesh V, Berning, Douglas E, Volkert, Wynn A, Ketring, Alan R, & Churchill, Robert. Conjugate and method for forming aminomethyl phosphorus conjugates. United States.
Katti, Kattesh V, Berning, Douglas E, Volkert, Wynn A, Ketring, Alan R, and Churchill, Robert. Fri .
"Conjugate and method for forming aminomethyl phosphorus conjugates". United States. https://www.osti.gov/servlets/purl/872500.
@article{osti_872500,
title = {Conjugate and method for forming aminomethyl phosphorus conjugates},
author = {Katti, Kattesh V and Berning, Douglas E and Volkert, Wynn A and Ketring, Alan R and Churchill, Robert},
abstractNote = {A method of forming phosphine-amine conjugates includes reacting a hydroxymethyl phosphine group of an amine-free first molecule with at least one free amine group of a second molecule to covalently bond the first molecule with the second molecule through an aminomethyl phosphorus linkage and the conjugates formed thereby.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {Fri Jan 01 00:00:00 EST 1999},
month = {Fri Jan 01 00:00:00 EST 1999}
}
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