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Title: Method of treating inflammatory diseases using a radiolabeled ferric hydroxide calloid

Abstract

A ferric hydroxide colloid having an alpha-emitting radionuclide essentially on the outer surfaces and a method of forming same. The method includes oxidizing a ferrous hydroxide to ferric hydroxide in the presence of a preselected radionuclide to form a colloid having the radionuclide on the outer surface thereof, and thereafter washing the colloid, and suspending the washed colloid in a suitable solution. The labelled colloid is useful in cancer therapy and for the treatment of inflamed joints.

Inventors:
 [1];  [2]
  1. Chicago, IL
  2. Glen Ellyn, IL
Issue Date:
Research Org.:
Argonne National Laboratory (ANL), Argonne, IL (United States)
OSTI Identifier:
868159
Patent Number(s):
5085848
Assignee:
United States of America as Represented by United States (Washington, DC)
Patent Classifications (CPCs):
A - HUMAN NECESSITIES A61 - MEDICAL OR VETERINARY SCIENCE A61K - PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
DOE Contract Number:  
W-31109-ENG-38
Resource Type:
Patent
Country of Publication:
United States
Language:
English
Subject:
method; treating; inflammatory; diseases; radiolabeled; ferric; hydroxide; calloid; colloid; alpha-emitting; radionuclide; essentially; outer; surfaces; forming; oxidizing; ferrous; presence; preselected; form; surface; thereafter; washing; suspending; washed; suitable; solution; labelled; useful; cancer; therapy; treatment; inflamed; joints; ferric hydroxide; outer surfaces; outer surface; cancer therapy; radionuclide essentially; suitable solution; thereafter washing; washed colloid; alpha-emitting radionuclide; preselected radionuclide; ferrous hydroxide; labelled colloid; inflamed joints; hydroxide colloid; emitting radionuclide; /424/252/600/

Citation Formats

Atcher, Robert W, and Hines, John J. Method of treating inflammatory diseases using a radiolabeled ferric hydroxide calloid. United States: N. p., 1992. Web.
Atcher, Robert W, & Hines, John J. Method of treating inflammatory diseases using a radiolabeled ferric hydroxide calloid. United States.
Atcher, Robert W, and Hines, John J. Wed . "Method of treating inflammatory diseases using a radiolabeled ferric hydroxide calloid". United States. https://www.osti.gov/servlets/purl/868159.
@article{osti_868159,
title = {Method of treating inflammatory diseases using a radiolabeled ferric hydroxide calloid},
author = {Atcher, Robert W and Hines, John J},
abstractNote = {A ferric hydroxide colloid having an alpha-emitting radionuclide essentially on the outer surfaces and a method of forming same. The method includes oxidizing a ferrous hydroxide to ferric hydroxide in the presence of a preselected radionuclide to form a colloid having the radionuclide on the outer surface thereof, and thereafter washing the colloid, and suspending the washed colloid in a suitable solution. The labelled colloid is useful in cancer therapy and for the treatment of inflamed joints.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {Wed Jan 01 00:00:00 EST 1992},
month = {Wed Jan 01 00:00:00 EST 1992}
}