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Title: Methods of treating Parkinson's disease using viral vectors

Abstract

Methods of delivering viral vectors, particularly recombinant adeno-associated virus (rAAV) virions, to the central nervous system (CNS) using convection enhanced delivery (CED) are provided. The rAAV virions include a nucleic acid sequence encoding a therapeutic polypeptide. The methods can be used for treating CNS disorders such as for treating Parkinson's Disease.

Inventors:
;
Issue Date:
Research Org.:
Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States)
Sponsoring Org.:
USDOE
OSTI Identifier:
1332285
Patent Number(s):
9492415
Application Number:
13/647,155
Assignee:
The Regents of the University of California (Oakland, CA)
Patent Classifications (CPCs):
C - CHEMISTRY C12 - BIOCHEMISTRY C12N - MICROORGANISMS OR ENZYMES
A - HUMAN NECESSITIES A61 - MEDICAL OR VETERINARY SCIENCE A61K - PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
DOE Contract Number:  
AC03-76SF00098; AC02-05CH11231
Resource Type:
Patent
Resource Relation:
Patent File Date: 2012 Oct 08
Country of Publication:
United States
Language:
English
Subject:
60 APPLIED LIFE SCIENCES; 59 BASIC BIOLOGICAL SCIENCES

Citation Formats

Bankiewicz, Krystof, and Cunningham, Janet. Methods of treating Parkinson's disease using viral vectors. United States: N. p., 2016. Web.
Bankiewicz, Krystof, & Cunningham, Janet. Methods of treating Parkinson's disease using viral vectors. United States.
Bankiewicz, Krystof, and Cunningham, Janet. Tue . "Methods of treating Parkinson's disease using viral vectors". United States. https://www.osti.gov/servlets/purl/1332285.
@article{osti_1332285,
title = {Methods of treating Parkinson's disease using viral vectors},
author = {Bankiewicz, Krystof and Cunningham, Janet},
abstractNote = {Methods of delivering viral vectors, particularly recombinant adeno-associated virus (rAAV) virions, to the central nervous system (CNS) using convection enhanced delivery (CED) are provided. The rAAV virions include a nucleic acid sequence encoding a therapeutic polypeptide. The methods can be used for treating CNS disorders such as for treating Parkinson's Disease.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {2016},
month = {11}
}

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Works referenced in this record:

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