Methods of treating Parkinson's disease using viral vectors
Abstract
Methods of delivering viral vectors, particularly recombinant adeno-associated virus (rAAV) virions, to the central nervous system (CNS) using convection enhanced delivery (CED) are provided. The rAAV virions include a nucleic acid sequence encoding a therapeutic polypeptide. The methods can be used for treating CNS disorders such as for treating Parkinson's Disease.
- Inventors:
- Issue Date:
- Research Org.:
- Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States)
- Sponsoring Org.:
- USDOE
- OSTI Identifier:
- 1332285
- Patent Number(s):
- 9492415
- Application Number:
- 13/647,155
- Assignee:
- The Regents of the University of California (Oakland, CA)
- Patent Classifications (CPCs):
-
C - CHEMISTRY C12 - BIOCHEMISTRY C12N - MICROORGANISMS OR ENZYMES
A - HUMAN NECESSITIES A61 - MEDICAL OR VETERINARY SCIENCE A61K - PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
- DOE Contract Number:
- AC03-76SF00098; AC02-05CH11231
- Resource Type:
- Patent
- Resource Relation:
- Patent File Date: 2012 Oct 08
- Country of Publication:
- United States
- Language:
- English
- Subject:
- 60 APPLIED LIFE SCIENCES; 59 BASIC BIOLOGICAL SCIENCES
Citation Formats
Bankiewicz, Krystof, and Cunningham, Janet. Methods of treating Parkinson's disease using viral vectors. United States: N. p., 2016.
Web.
Bankiewicz, Krystof, & Cunningham, Janet. Methods of treating Parkinson's disease using viral vectors. United States.
Bankiewicz, Krystof, and Cunningham, Janet. Tue .
"Methods of treating Parkinson's disease using viral vectors". United States. https://www.osti.gov/servlets/purl/1332285.
@article{osti_1332285,
title = {Methods of treating Parkinson's disease using viral vectors},
author = {Bankiewicz, Krystof and Cunningham, Janet},
abstractNote = {Methods of delivering viral vectors, particularly recombinant adeno-associated virus (rAAV) virions, to the central nervous system (CNS) using convection enhanced delivery (CED) are provided. The rAAV virions include a nucleic acid sequence encoding a therapeutic polypeptide. The methods can be used for treating CNS disorders such as for treating Parkinson's Disease.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {2016},
month = {11}
}
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