Thiophene metabolism by E. coli
The objective of this project is to investigate the mechanism of degradation of sulfur containing heterocyclic molecules such as those found in coal, by mutants of Escherichia coli K-12. We previously isolated multiple mutants of E. coli which were selected for improved oxidation of furan and thiophene derivatives. We have focused on the thdA mutation in our subsequent research as it appears to be of central importance in thiophene oxidation. We hope that analysis of the thd genes of E. coli will lead to improvement of our thiophene metabolizing bacterial strains. 1 tab.
- Research Organization:
- Southern Illinois Univ., Carbondale, IL (USA). Dept. of Microbiology
- Sponsoring Organization:
- DOE/FE
- DOE Contract Number:
- FG22-87PC79912
- OSTI ID:
- 6855589
- Report Number(s):
- DOE/PC/79912-12; ON: DE91000851
- Country of Publication:
- United States
- Language:
- English
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Related Subjects
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59 BASIC BIOLOGICAL SCIENCES
THIOPHENE
BIODEGRADATION
COAL
DESULFURIZATION
DNA SEQUENCING
ESCHERICHIA COLI
METABOLISM
MUTANTS
PROGRESS REPORT
BACTERIA
CARBONACEOUS MATERIALS
CHEMICAL REACTIONS
DECOMPOSITION
DOCUMENT TYPES
ENERGY SOURCES
FOSSIL FUELS
FUELS
HETEROCYCLIC COMPOUNDS
MATERIALS
MICROORGANISMS
ORGANIC COMPOUNDS
ORGANIC SULFUR COMPOUNDS
STRUCTURAL CHEMICAL ANALYSIS
010402* - Coal
Lignite
& Peat- Purification & Upgrading
550700 - Microbiology