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Title: Thiophene metabolism by E. coli

Technical Report ·
DOI:https://doi.org/10.2172/6855589· OSTI ID:6855589

The objective of this project is to investigate the mechanism of degradation of sulfur containing heterocyclic molecules such as those found in coal, by mutants of Escherichia coli K-12. We previously isolated multiple mutants of E. coli which were selected for improved oxidation of furan and thiophene derivatives. We have focused on the thdA mutation in our subsequent research as it appears to be of central importance in thiophene oxidation. We hope that analysis of the thd genes of E. coli will lead to improvement of our thiophene metabolizing bacterial strains. 1 tab.

Research Organization:
Southern Illinois Univ., Carbondale, IL (USA). Dept. of Microbiology
Sponsoring Organization:
DOE/FE
DOE Contract Number:
FG22-87PC79912
OSTI ID:
6855589
Report Number(s):
DOE/PC/79912-12; ON: DE91000851
Country of Publication:
United States
Language:
English