Thiophene metabolism by E. coli

Technical Report · Mon Jan 01 04:00:00 EST 1990

DOI:https://doi.org/10.2172/6296900· OSTI ID:6296900

Clark, D P

The objective of this project is to investigate the mechanism of degradation of sulfur containing heterocyclic molecules by mutants of Escherichia coli K-12. We previously isolated multiple mutants of E. coli which were selected for improved oxidation of furan and thiophene derivatives. We have focused on the thdA mutation in our subsequent research as it appears to be of central importance in thiophene oxidation. We hope that analysis of the thd gene of E. coli will lead to improvement of our thiophene metabolizing bacterial strains.

• Research Organization: Southern Illinois Univ., Carbondale, IL (USA). Dept. of Microbiology
• Sponsoring Organization: DOE/FE
• DOE Contract Number: FG22-87PC79912
• OSTI ID: 6296900
• Report Number(s): DOE/PC/79912-13; ON: DE91005924
• Country of Publication: United States
• Language: English

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59 BASIC BIOLOGICAL SCIENCES
BACTERIA
BIODEGRADATION
CARBONACEOUS MATERIALS
CHEMICAL REACTIONS
COAL
CULTURE MEDIA
DECOMPOSITION
DESULFURIZATION
DOCUMENT TYPES
ENERGY SOURCES
ESCHERICHIA COLI
FOSSIL FUELS
FUELS
GENES
HETEROCYCLIC COMPOUNDS
MATERIALS
MICROORGANISMS
MUTANTS
ORGANIC COMPOUNDS
ORGANIC SULFUR COMPOUNDS
PROGRESS REPORT
SULFONES
THIOPHENE