Thiophene metabolism by E. coli

Technical Report · Mon Jan 01 04:00:00 EST 1990

DOI:https://doi.org/10.2172/6855589· OSTI ID:6855589

Clark, D P

The objective of this project is to investigate the mechanism of degradation of sulfur containing heterocyclic molecules such as those found in coal, by mutants of Escherichia coli K-12. We previously isolated multiple mutants of E. coli which were selected for improved oxidation of furan and thiophene derivatives. We have focused on the thdA mutation in our subsequent research as it appears to be of central importance in thiophene oxidation. We hope that analysis of the thd genes of E. coli will lead to improvement of our thiophene metabolizing bacterial strains. 1 tab.

• Research Organization: Southern Illinois Univ., Carbondale, IL (USA). Dept. of Microbiology
• Sponsoring Organization: DOE/FE
• DOE Contract Number: FG22-87PC79912
• OSTI ID: 6855589
• Report Number(s): DOE/PC/79912-12; ON: DE91000851
• Country of Publication: United States
• Language: English

Related Subjects

01 COAL, LIGNITE, AND PEAT
010402* -- Coal
Lignite
& Peat-- Purification & Upgrading
550700 -- Microbiology
59 BASIC BIOLOGICAL SCIENCES
BACTERIA
BIODEGRADATION
CARBONACEOUS MATERIALS
CHEMICAL REACTIONS
COAL
DECOMPOSITION
DESULFURIZATION
DNA SEQUENCING
DOCUMENT TYPES
ENERGY SOURCES
ESCHERICHIA COLI
FOSSIL FUELS
FUELS
HETEROCYCLIC COMPOUNDS
MATERIALS
METABOLISM
MICROORGANISMS
MUTANTS
ORGANIC COMPOUNDS
ORGANIC SULFUR COMPOUNDS
PROGRESS REPORT
STRUCTURAL CHEMICAL ANALYSIS
THIOPHENE