Solution target for cyclotron production of radiometals

DeGrado, Timothy R.; Pandey, Mukesh K.; Byrne, John

Title: Solution target for cyclotron production of radiometals

Patent · Tue Dec 31 00:00:00 EST 2019

OSTI ID:1600451

DeGrado, Timothy R.; Pandey, Mukesh K.; Byrne, John

Methods of producing and isolating 68Ga, 89Zr, 64Cu, 63Zn, 86Y, 61Cu, 99mTc, 45Ti, 13N, 52Mn, or 44Sc and solution targets for use in the methods are disclosed. The methods of producing 68Ga, 89Zr, 64Cu, 63Zn, 86Y, 61Cu, 99mTc, 45Ti, 13N, 52Mn, or 44Sc include irradiating a closed target system with a proton beam. The closed target system can include a solution target. The methods of producing isolated 68Ga, 89Zr, 64Cu, 63Zn, 86Y, 61CU, 99mTC, 45-Ti, 52Mn, or 44Sc by ion exchange chromatography. An example solution target includes a target body including a target cavity for receiving the target material; a housing defining a passageway for directing a particle beam at the target cavity; a target window for covering an opening of the target cavity; and a coolant gas flow path disposed in the passageway upstream of the target window.

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Research Organization:: Mayo Foundation for Medical Education and Research, Rochester, MN (United States); Brigham and Women's Hospital, Inc., Boston, MA (United States)

Sponsoring Organization:: USDOE

DOE Contract Number:: SC0008947

Assignee:: Mayo Foundation for Medical Education and Research (Rochester, MN); Brigham and Women's Hospital, Inc. (Boston, MA)

Patent Number(s):: 10,522,261

Application Number:: 15/311,052

OSTI ID:: 1600451

Resource Relation:: Patent File Date: 05/15/2015

Country of Publication:: United States

Language:: English

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