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Title: Tumor suppressor molecules and methods of use

Patent ·
OSTI ID:1175018

The invention provides substantially pure tumor suppressor nucleic acid molecules and tumor suppressor polypeptides. The invention also provides hairpin ribozymes and antibodies selective for these tumor suppressor molecules. Also provided are methods of detecting a neoplastic cell in a sample using detectable agents specific for the tumor suppressor nucleic acids and polypeptides.

Research Organization:
Immusol, Inc., San Diego, CA (United States)
Sponsoring Organization:
USDOE
DOE Contract Number:
FG03-98ER62624
Assignee:
Immusol, Inc. (San Diego, CA)
Patent Number(s):
6,787,646
Application Number:
09/438,917
OSTI ID:
1175018
Country of Publication:
United States
Language:
English

References (11)

Events calendar journal April 1993
Cloning and Characterization of peter pan , a Novel Drosophila Gene Required for Larval Growth journal June 1999
Expression of a p16 INK4a -specific ribozyme downmodulates p16 INK4a abundance and accelerates cell proliferation journal September 1998
Transforming growth factor alpha: mutation of aspartic acid 47 and leucine 48 results in different biological activities. journal March 1988
Identification of cDNAs for Sox-4, an HMG-Box Protein, and a Novel Human Homolog of Yeast Splicing Factor SSF-1 Differentially Regulated during Apoptosis Induced by Prostaglandin A2/Δ12-PGJ2 in Hep3B Cells journal June 1999
Identification and Validation of a Gene Involved in Anchorage-Independent Cell Growth Control Using a Library of Randomized Hairpin Ribozymes journal June 2000
GenBank journal January 1996
Christmas craft journal November 1998
The Role of P53 in Human Cancer journal February 2001
Cloning, Genomic Organization, and Tissue Distribution of Human Ssf-1 journal August 2000
GenBank journal January 1997