Generating electrospray from microchip devices using electroosmotic pumping
- Oak Ridge National Lab., TN (United States)
A method of generating electrospray from solutions emerging from small channels etched on planer substrates in described. The fluids are delivered using electroosmotically induced pressures and are sprayed electrostatically from the terminus of a channel by applying an electrical potential of sufficient amplitude to generate the electrospray between the microchip and a conductor spaced from the channel terminus. No major modification of the microchip is required other than to expose a channel opening. The principles that regulate the fluid delivery are described and demonstrated. A spectrum for a test compound, tetrabutylammonium iodide, that was continuously electrophoresed was obtained by coupling the microchip to an ion trap mass spectrometer. 35 refs., 6 figs.
- DOE Contract Number:
- AC05-96OR22464
- OSTI ID:
- 466365
- Journal Information:
- Analytical Chemistry (Washington), Vol. 69, Issue 6; Other Information: PBD: 15 Mar 1997
- Country of Publication:
- United States
- Language:
- English
Similar Records
A microfabricated electroosmotic pump coupled to a gas-diffusion microchip for flow injection analysis of ammonia
Open channel electrochromatography on a microchip