A microfabricated electroosmotic pump coupled to a gas-diffusion microchip for flow injection analysis of ammonia

Zhu, Zaifang; Lu, Joann J.; Almeida, M. Ines G.  S.; Pu, Qiaosheng; Kolev, Spas D.; Liu, Shaorong

doi:10.1007/s00604-014-1410-7

A microfabricated electroosmotic pump coupled to a gas-diffusion microchip for flow injection analysis of ammonia

Journal Article · Wed Dec 03 00:00:00 EST 2014 · Mikrochimica Acta

DOI:https://doi.org/10.1007/s00604-014-1410-7· OSTI ID:1337180

Zhu, Zaifang ^[1]; Lu, Joann J. ^[2]; Almeida, M. Ines G. S. ^[3]; Pu, Qiaosheng ^[4]; Kolev, Spas D. ^[3]; Liu, Shaorong ^[2]

Univ. of Oklahoma, Norman, OK (United States). Dept. of Chemistry and Biochemistry; University of Oklahoma
Univ. of Oklahoma, Norman, OK (United States). Dept. of Chemistry and Biochemistry
Univ. of Melbourne (Australia). School of Chemistry
Lanzhou Univ. (China). College of Chemistry and Chemical Engineering

Here we have microfabricated two functional components toward developing a microchip flow injection analysis (FIA) system, i.e., an open-channel electroosmotic pump and a gas-diffusion chip, consisting of two microfabricated glass wafers and a porous polytetrafluoroethylene membrane. This is the first application of gas-diffusion separation in a microchip FIA system. To demonstrate the feasibility of using these two components for performing gas-diffusion FIA, we have incorporated them together with a regular FIA injection valve and a capillary electrophoresis absorbance detector in a flow injection system for determination of ammonia in environmental water samples. This system has a limit of detection of 0.10 mg L^-1 NH₃, with a good repeatability (relative standard deviation of less than 5 % for 4.0 mg L^-1 NH₃). We also discuss parameters affecting its performance.

View Accepted Manuscript (DOE)

Research Organization:: MicroChem Solutions, Norman, OK (United States)

Sponsoring Organization:: NIH; NSF; USDOE

Contributing Organization:: University of Oklahoma

Grant/Contract Number:: SC0006351

OSTI ID:: 1337180

Alternate ID(s):: OSTI ID: 22451413

Journal Information:: Mikrochimica Acta, Journal Name: Mikrochimica Acta Journal Issue: 5-6 Vol. 182; ISSN 0026-3672

Publisher:: SpringerCopyright Statement

Country of Publication:: United States

Language:: English

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Development and application of a portable fluorescence detector for shipboard analysis of ammonium in estuarine and coastal waters Zhu, Yong; Chen, Jianfang; Shi, Xiaolai Analytical Methods, Vol. 10, Issue 15 https://doi.org/10.1039/c8ay00438b	journal	January 2018
The spin-coating-based immobilization of ZnTPP-dyed cation exchange resin microbeads for reversible ammonia detection Zhou, Hao; Yang, Zheng; Cen, Kefa Analytical Methods, Vol. 11, Issue 16 https://doi.org/10.1039/c9ay00171a	journal	January 2019
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Rapid on-chip quantification of ammonia nitrogen based on a ‘flow and react’ mechanism Jiang, Huiyun; Sun, Bing; Zhu, Hongwei Taylor & Francis https://doi.org/10.6084/m9.figshare.11841177	text	January 2020
Rapid on-chip quantification of ammonia nitrogen based on a ‘flow and react’ mechanism Jiang, Huiyun; Sun, Bing; Zhu, Hongwei Taylor & Francis https://doi.org/10.6084/m9.figshare.11841177.v1	text	January 2020

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Ammonia
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Microchip
Microfluidic device

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