DOE PAGES title logo U.S. Department of Energy
Office of Scientific and Technical Information

Title: Decoupling copolymer, lipid and carbon nanotube interactions in hybrid, biomimetic vesicles

Abstract

Bilayer vesicles that mimic a real biological cell can be tailored to carry out a specific function by manipulating the molecular composition of the amphiphiles.

Authors:
ORCiD logo [1];  [1];  [1];  [1];  [1];  [1];  [1];  [1];  [1];  [1]
  1. Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States)
Publication Date:
Research Org.:
SLAC National Accelerator Laboratory (SLAC), Menlo Park, CA (United States); Lawrence Livermore National Laboratory (LLNL), Livermore, CA (United States)
Sponsoring Org.:
USDOE National Nuclear Security Administration (NNSA)
OSTI Identifier:
1616992
Alternate Identifier(s):
OSTI ID: 1604106; OSTI ID: 1716590
Report Number(s):
LLNL-JRNL-797277
Journal ID: ISSN 2040-3364; NANOHL; TRN: US2106698
Grant/Contract Number:  
AC02-76SF00515; AC52-07NA27344; 18-ERD-035; SCW0972
Resource Type:
Accepted Manuscript
Journal Name:
Nanoscale
Additional Journal Information:
Journal Volume: 12; Journal Issue: 11; Journal ID: ISSN 2040-3364
Publisher:
Royal Society of Chemistry
Country of Publication:
United States
Language:
English
Subject:
59 BASIC BIOLOGICAL SCIENCES

Citation Formats

Hammons, Joshua A., Ingólfsson, Helgi I., Lee, Jonathan R. I., Carpenter, Tim S., Sanborn, Jeremy, Tunuguntla, Ramya, Yao, Yun-Chiao, Weiss, Thomas M., Noy, Aleksandr, and Van Buuren, Tony. Decoupling copolymer, lipid and carbon nanotube interactions in hybrid, biomimetic vesicles. United States: N. p., 2020. Web. doi:10.1039/c9nr09973e.
Hammons, Joshua A., Ingólfsson, Helgi I., Lee, Jonathan R. I., Carpenter, Tim S., Sanborn, Jeremy, Tunuguntla, Ramya, Yao, Yun-Chiao, Weiss, Thomas M., Noy, Aleksandr, & Van Buuren, Tony. Decoupling copolymer, lipid and carbon nanotube interactions in hybrid, biomimetic vesicles. United States. https://doi.org/10.1039/c9nr09973e
Hammons, Joshua A., Ingólfsson, Helgi I., Lee, Jonathan R. I., Carpenter, Tim S., Sanborn, Jeremy, Tunuguntla, Ramya, Yao, Yun-Chiao, Weiss, Thomas M., Noy, Aleksandr, and Van Buuren, Tony. Thu . "Decoupling copolymer, lipid and carbon nanotube interactions in hybrid, biomimetic vesicles". United States. https://doi.org/10.1039/c9nr09973e. https://www.osti.gov/servlets/purl/1616992.
@article{osti_1616992,
title = {Decoupling copolymer, lipid and carbon nanotube interactions in hybrid, biomimetic vesicles},
author = {Hammons, Joshua A. and Ingólfsson, Helgi I. and Lee, Jonathan R. I. and Carpenter, Tim S. and Sanborn, Jeremy and Tunuguntla, Ramya and Yao, Yun-Chiao and Weiss, Thomas M. and Noy, Aleksandr and Van Buuren, Tony},
abstractNote = {Bilayer vesicles that mimic a real biological cell can be tailored to carry out a specific function by manipulating the molecular composition of the amphiphiles.},
doi = {10.1039/c9nr09973e},
journal = {Nanoscale},
number = 11,
volume = 12,
place = {United States},
year = {Thu Mar 05 00:00:00 EST 2020},
month = {Thu Mar 05 00:00:00 EST 2020}
}

Journal Article:
Free Publicly Available Full Text
Publisher's Version of Record

Citation Metrics:
Cited by: 5 works
Citation information provided by
Web of Science

Save / Share:

Works referenced in this record:

Transferable MARTINI Model of Poly(ethylene Oxide)
journal, July 2018

  • Grunewald, Fabian; Rossi, Giulia; de Vries, Alex H.
  • The Journal of Physical Chemistry B, Vol. 122, Issue 29
  • DOI: 10.1021/acs.jpcb.8b04760

Biomimetic membranes: A review
journal, March 2014


High-Yield Synthesis and Optical Properties of Carbon Nanotube Porins
journal, January 2017

  • Tunuguntla, Ramya H.; Chen, Xi; Belliveau, Allison
  • The Journal of Physical Chemistry C, Vol. 121, Issue 5
  • DOI: 10.1021/acs.jpcc.6b11658

Bioelectronic silicon nanowire devices using functional membrane proteins
journal, August 2009

  • Misra, N.; Martinez, J. A.; Huang, S. -C. J.
  • Proceedings of the National Academy of Sciences, Vol. 106, Issue 33
  • DOI: 10.1073/pnas.0904850106

Small is beautiful: Surprising nanoparticles
journal, April 2016


Models to analyze small-angle neutron scattering from unilamellar lipid vesicles
journal, May 2004


Modulation of phase separation at the micron scale and nanoscale in giant polymer/lipid hybrid unilamellar vesicles (GHUVs)
journal, January 2017

  • Dao, Thi Phuong Tuyen; Fernandes, Fabio; Ibarboure, Emmanuel
  • Soft Matter, Vol. 13, Issue 3
  • DOI: 10.1039/C6SM01625A

Self-assembly as a key player for materials nanoarchitectonics
journal, January 2019

  • Ariga, Katsuhiko; Nishikawa, Michihiro; Mori, Taizo
  • Science and Technology of Advanced Materials, Vol. 20, Issue 1
  • DOI: 10.1080/14686996.2018.1553108

Structure of lipid bilayers
journal, November 2000

  • Nagle, John F.; Tristram-Nagle, Stephanie
  • Biochimica et Biophysica Acta (BBA) - Reviews on Biomembranes, Vol. 1469, Issue 3
  • DOI: 10.1016/S0304-4157(00)00016-2

Structural Properties of Archaeal Lipid Bilayers: Small-Angle X-ray Scattering and Molecular Dynamics Simulation Study
journal, July 2014

  • Polak, Andraž; Tarek, Mounir; Tomšič, Matija
  • Langmuir, Vol. 30, Issue 28
  • DOI: 10.1021/la5014208

Real-time dynamics of carbon nanotube porins in supported lipid membranes visualized by high-speed atomic force microscopy
journal, June 2017

  • Zhang, Yuliang; Tunuguntla, Ramya H.; Choi, Pyung-On
  • Philosophical Transactions of the Royal Society B: Biological Sciences, Vol. 372, Issue 1726
  • DOI: 10.1098/rstb.2016.0226

Scattering Density Profile Model of POPG Bilayers As Determined by Molecular Dynamics Simulations and Small-Angle Neutron and X-ray Scattering Experiments
journal, December 2011

  • Kučerka, Norbert; Holland, Bryan W.; Gray, Chris G.
  • The Journal of Physical Chemistry B, Vol. 116, Issue 1
  • DOI: 10.1021/jp208920h

Supramolecular Self-Assembly of Lipid Derivatives on Carbon Nanotubes
journal, May 2003


Phase Separation and Nanodomain Formation in Hybrid Polymer/Lipid Vesicles
journal, January 2015

  • Dao, T. P. Tuyen; Fernandes, F.; Er-Rafik, M.
  • ACS Macro Letters, Vol. 4, Issue 2
  • DOI: 10.1021/mz500748f

Effect of double tailed cationic surfactants on the physicochemical behavior of hybrid vesicles
journal, January 2016

  • Koirala, Suraj; Roy, Biplab; Guha, Pritam
  • RSC Advances, Vol. 6, Issue 17
  • DOI: 10.1039/C5RA17774J

Stochastic transport through carbon nanotubes in lipid bilayers and live cell membranes
journal, October 2014

  • Geng, Jia; Kim, Kyunghoon; Zhang, Jianfei
  • Nature, Vol. 514, Issue 7524
  • DOI: 10.1038/nature13817

Martini straight: Boosting performance using a shorter cutoff and GPUs
journal, February 2016

  • de Jong, Djurre H.; Baoukina, Svetlana; Ingólfsson, Helgi I.
  • Computer Physics Communications, Vol. 199
  • DOI: 10.1016/j.cpc.2015.09.014

Tailored drug-release from multi-functional polymer-peptide hybrid vesicles
journal, January 2015


Highly Efficient Biocompatible Single Silicon Nanowire Electrodes with Functional Biological Pore Channels
journal, March 2009

  • Martinez, Julio A.; Misra, Nipun; Wang, Yinmin
  • Nano Letters, Vol. 9, Issue 3
  • DOI: 10.1021/nl8036504

Mixed Hybrid Lipid/Polymer Vesicles as a Novel Membrane Platform
journal, October 2015

  • Schulz, Matthias; Binder, Wolfgang H.
  • Macromolecular Rapid Communications, Vol. 36, Issue 23
  • DOI: 10.1002/marc.201500344

Hybrid lipid/polymer giant unilamellar vesicles: effects of incorporated biocompatible PIB–PEO block copolymers on vesicle properties
journal, January 2011

  • Schulz, Matthias; Glatte, Daniela; Meister, Annette
  • Soft Matter, Vol. 7, Issue 18
  • DOI: 10.1039/c1sm05725a

Curvature Effect on the Structure of Phospholipid Bilayers
journal, January 2007

  • Kučerka, Norbert; Pencer, Jeremy; Sachs, Jonathan N.
  • Langmuir, Vol. 23, Issue 3
  • DOI: 10.1021/la062455t

Mimicking the cell membrane with block copolymer membranes
journal, March 2012

  • Zhang, Xiaoyan; Tanner, Pascal; Graff, Alexandra
  • Journal of Polymer Science Part A: Polymer Chemistry, Vol. 50, Issue 12
  • DOI: 10.1002/pola.26000

Synthesis, lipid membrane incorporation, and ion permeability testing of carbon nanotube porins
journal, September 2016

  • Tunuguntla, Ramya H.; Escalada, Artur; A. Frolov, Vadim
  • Nature Protocols, Vol. 11, Issue 10
  • DOI: 10.1038/nprot.2016.119

Molecular dynamics simulations of carbon nanotube porins in lipid bilayers
journal, January 2018

  • Vögele, Martin; Köfinger, Jürgen; Hummer, Gerhard
  • Faraday Discussions, Vol. 209
  • DOI: 10.1039/C8FD00011E

Hybrid polymer/lipid vesicles: state of the art and future perspectives
journal, October 2013


Durable proteo-hybrid vesicles for the extended functional lifetime of membrane proteins in bionanotechnology
journal, January 2016

  • Khan, Sanobar; Li, Mengqiu; Muench, Stephen P.
  • Chemical Communications, Vol. 52, Issue 73
  • DOI: 10.1039/C6CC04207D

Comparing Membrane Simulations to Scattering Experiments: Introducing the SIMtoEXP Software
journal, April 2010

  • Kučerka, Norbert; Katsaras, John; Nagle, John F.
  • Journal of Membrane Biology, Vol. 235, Issue 1
  • DOI: 10.1007/s00232-010-9254-5

Carbon nanotube self-assembly with lipids and detergent: a molecular dynamics study
journal, December 2008


Computational ‘microscopy’ of cellular membranes
journal, January 2016

  • Ingólfsson, Helgi I.; Arnarez, Clément; Periole, Xavier
  • Journal of Cell Science, Vol. 129, Issue 2
  • DOI: 10.1242/jcs.176040

Hybrid polymer/lipid vesicles: fine control of the lipid and polymer distribution in the binary membrane
journal, January 2012

  • Chemin, Maud; Brun, Pierre-Marie; Lecommandoux, Sébastien
  • Soft Matter, Vol. 8, Issue 10
  • DOI: 10.1039/c2sm07188f

A reconstitution method for integral membrane proteins in hybrid lipid-polymer vesicles for enhanced functional durability
journal, September 2018


Hybrid, Nanoscale Phospholipid/Block Copolymer Vesicles
journal, September 2013


Canonical sampling through velocity rescaling
journal, January 2007

  • Bussi, Giovanni; Donadio, Davide; Parrinello, Michele
  • The Journal of Chemical Physics, Vol. 126, Issue 1
  • DOI: 10.1063/1.2408420

Enhanced water permeability and tunable ion selectivity in subnanometer carbon nanotube porins
journal, August 2017

  • Tunuguntla, Ramya H.; Henley, Robert Y.; Yao, Yun-Chiao
  • Science, Vol. 357, Issue 6353
  • DOI: 10.1126/science.aan2438

Diameter of Carbon Nanotube-Directed Self-Assembly of Amphiphilic Block Copolymers
journal, May 2019

  • Wang, Zihao; Tao, Susu; Chu, Yanyan
  • Materials, Vol. 12, Issue 10
  • DOI: 10.3390/ma12101606

Aggregation and Self-Assembly of Amphiphilic Block Copolymers in Aqueous Dispersions of Carbon Nanotubes
journal, May 2008

  • Shvartzman-Cohen, Rina; Florent, Marc; Goldfarb, Daniella
  • Langmuir, Vol. 24, Issue 9
  • DOI: 10.1021/la703782g

Biomimetic Conducting Polymers: Synthesis, Materials, Properties, Functions, and Devices
journal, July 2013


Ultrafast proton transport in sub-1-nm diameter carbon nanotube porins
journal, April 2016

  • Tunuguntla, Ramya H.; Allen, Frances I.; Kim, Kyunghoon
  • Nature Nanotechnology, Vol. 11, Issue 7
  • DOI: 10.1038/nnano.2016.43

Carbon Nanotube Porins in Amphiphilic Block Copolymers as Fully Synthetic Mimics of Biological Membranes
journal, October 2018

  • Sanborn, Jeremy R.; Chen, Xi; Yao, Yun-Chiao
  • Advanced Materials, Vol. 30, Issue 51
  • DOI: 10.1002/adma.201803355

Polymorphic transitions in single crystals: A new molecular dynamics method
journal, December 1981

  • Parrinello, M.; Rahman, A.
  • Journal of Applied Physics, Vol. 52, Issue 12
  • DOI: 10.1063/1.328693

Biological small-angle X-ray scattering facility at the Stanford Synchrotron Radiation Laboratory
journal, April 2007

  • Smolsky, Igor L.; Liu, Ping; Niebuhr, Marc
  • Journal of Applied Crystallography, Vol. 40, Issue s1
  • DOI: 10.1107/S0021889807009624

The MARTINI Force Field:  Coarse Grained Model for Biomolecular Simulations
journal, July 2007

  • Marrink, Siewert J.; Risselada, H. Jelger; Yefimov, Serge
  • The Journal of Physical Chemistry B, Vol. 111, Issue 27
  • DOI: 10.1021/jp071097f

An integrated high-throughput data acquisition system for biological solution X-ray scattering studies
journal, March 2012

  • Martel, Anne; Liu, Ping; Weiss, Thomas M.
  • Journal of Synchrotron Radiation, Vol. 19, Issue 3
  • DOI: 10.1107/S0909049512008072

Order Parameters and Areas in Fluid-Phase Oriented Lipid Membranes Using Wide Angle X-Ray Scattering
journal, July 2008

  • Mills, Thalia T.; Toombes, Gilman E. S.; Tristram-Nagle, Stephanie
  • Biophysical Journal, Vol. 95, Issue 2
  • DOI: 10.1529/biophysj.107.127845

Giant Phospholipid/Block Copolymer Hybrid Vesicles: Mixing Behavior and Domain Formation
journal, January 2011

  • Nam, Jin; Beales, Paul A.; Vanderlick, T. Kyle
  • Langmuir, Vol. 27, Issue 1
  • DOI: 10.1021/la103428g

Structure of Carbon Nanotube Porins in Lipid Bilayers: An in Situ Small-Angle X-ray Scattering (SAXS) Study
journal, June 2016


X-ray diffraction study of a polybutadiene, side chain, mesomorphic polymer
journal, January 1989


Effective interactions in lysozyme aqueous solutions: A small-angle neutron scattering and computer simulation study
journal, January 2012

  • Abramo, M. C.; Caccamo, C.; Costa, D.
  • The Journal of Chemical Physics, Vol. 136, Issue 3
  • DOI: 10.1063/1.3677186

Computational Lipidomics with insane : A Versatile Tool for Generating Custom Membranes for Molecular Simulations
journal, April 2015

  • Wassenaar, Tsjerk A.; Ingólfsson, Helgi I.; Böckmann, Rainer A.
  • Journal of Chemical Theory and Computation, Vol. 11, Issue 5
  • DOI: 10.1021/acs.jctc.5b00209

Structure and polymorphism of the hydrocarbon chains of lipids: A study of lecithin-water phases
journal, April 1973