Title: Ordered three-dimensional nanomaterials using DNA-prescribed and valence-controlled material voxels

Abstract

The ability to organize nanoscale objects into well-defined three-dimensional (3D) arrays can translate advances in nanoscale synthesis into targeted material fabrication. Despite successes in nanoparticle assembly, most extant methods are system specific and not fully compatible with biomolecules. As such, here, we report a platform for creating distinct 3D ordered arrays from different nanomaterials using DNA-prescribed and valence-controlled material voxels. These material voxels consist of 3D DNA frames that integrate nano-objects within their scaffold, thus enabling the object’s valence and coordination to be determined by the frame’s vertices, which can bind to each other through hybridization. Such DNA material voxels define the lattice symmetry through the spatially prescribed valence decoupling the 3D assembly process from the nature of the nanocomponents, such as their intrinsic properties and shapes. We show this by assembling metallic and semiconductor nanoparticles and also protein superlattices. We support the technological potential of such an assembly approach by fabricating light-emitting 3D arrays with diffraction-limited spectral purity and 3D enzymatic arrays with increased activity.

Authors:

Tian, Ye ^[1]; Lhermitte, Julien R. ^[2]; Bai, Lin  ^[3];

• Search DOE PAGES for author "Bai, Lin"
• Search DOE PAGES for ORCID "0000-0002-7535-7819"

Vo, Thi ^[4]; Xin, Huolin L.  ^[2];

• Search DOE PAGES for author "Xin, Huolin L."
• Search DOE PAGES for ORCID "0000-0002-6521-868X"

Li, Huilin  ^[3];

• Search DOE PAGES for author "Li, Huilin"
• Search DOE PAGES for ORCID "0000-0001-8085-8928"

Li, Ruipeng ^[5]; Fukuto, Masafumi ^[5]; Yager, Kevin G. ^[2]; Kahn, Jason S. ^[4]; Xiong, Yan ^[4]; Minevich, Brian ^[4]; Kumar, Sanat K. ^[4]; Gang, Oleg  ^[6]

• Search DOE PAGES for author "Gang, Oleg"
• Search DOE PAGES for ORCID "0000-0001-5534-3121"

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+ Show Author Affiliations

1. Brookhaven National Lab. (BNL), Upton, NY (United States). Center for Functional Nanomaterials (CFN); Nanjing Univ. (China)
2. Brookhaven National Lab. (BNL), Upton, NY (United States). Center for Functional Nanomaterials (CFN)
3. Van Andel Inst., Grand Rapids, MI (United States)
4. Columbia Univ., New York, NY (United States)
5. Brookhaven National Lab. (BNL), Upton, NY (United States). National Synchrotron Light Source
6. Brookhaven National Lab. (BNL), Upton, NY (United States). Center for Functional Nanomaterials (CFN); Columbia Univ., New York, NY (United States)

Publication Date:

Mon Jan 13 00:00:00 EST 2020

Research Org.:

Brookhaven National Laboratory (BNL), Upton, NY (United States)

Sponsoring Org.:

Jiangsu Youth Fund of China; Fundamental Research Funds for the Central Universities (China); National Institutes of Health (NIH); USDOE Office of Science (SC), Basic Energy Sciences (BES). Scientific User Facilities Division

OSTI Identifier:

1600469

Report Number(s):

BNL-213632-2020-JAAM
Journal ID: ISSN 1476-1122

Grant/Contract Number:  

SC0012704; BK20180337; 14380151; GM111472; GM124170; SC0008772

Resource Type:

Accepted Manuscript

Journal Name:

Nature Materials

Additional Journal Information:

Journal Volume: 19; Journal Issue: 7; Journal ID: ISSN 1476-1122

Publisher:

Springer Nature - Nature Publishing Group

Country of Publication:

United States

Language:

English

Subject:

77 NANOSCIENCE AND NANOTECHNOLOGY; Nanoparticles; Nanoscale materials; Organizing materials with DNA; Self-assembly