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Title: Id-1 and Id-2 genes and products as markers of epithelial cancer

Abstract

A method for detection and prognosis of breast cancer and other types of cancer. The method comprises detecting expression, if any, for both an Id-1 and an Id-2 genes, or the ratio thereof, of gene products in samples of breast tissue obtained from a patient. When expressed, Id-1 gene is a prognostic indicator that breast cancer cells are invasive and metastatic, whereas Id-2 gene is a prognostic indicator that breast cancer cells are localized and noninvasive in the breast tissue.

Inventors:
 [1];  [2]
  1. El Cerrito, CA
  2. Berkeley, CA
Issue Date:
Research Org.:
Univ. of California (United States)
Sponsoring Org.:
USDOE
OSTI Identifier:
984513
Patent Number(s):
7429457
Application Number:
09/952,534
Assignee:
The Regents of the University of California (Oakland, CA); California Pacific Medical Center (San Francisco, CA)
Patent Classifications (CPCs):
G - PHYSICS G01 - MEASURING G01N - INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
C - CHEMISTRY C12 - BIOCHEMISTRY C12Q - MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS
DOE Contract Number:  
AC03-76SF00098
Resource Type:
Patent
Country of Publication:
United States
Language:
English
Subject:
60 APPLIED LIFE SCIENCES

Citation Formats

Desprez, Pierre-Yves, and Campisi, Judith. Id-1 and Id-2 genes and products as markers of epithelial cancer. United States: N. p., 2008. Web.
Desprez, Pierre-Yves, & Campisi, Judith. Id-1 and Id-2 genes and products as markers of epithelial cancer. United States.
Desprez, Pierre-Yves, and Campisi, Judith. Tue . "Id-1 and Id-2 genes and products as markers of epithelial cancer". United States. https://www.osti.gov/servlets/purl/984513.
@article{osti_984513,
title = {Id-1 and Id-2 genes and products as markers of epithelial cancer},
author = {Desprez, Pierre-Yves and Campisi, Judith},
abstractNote = {A method for detection and prognosis of breast cancer and other types of cancer. The method comprises detecting expression, if any, for both an Id-1 and an Id-2 genes, or the ratio thereof, of gene products in samples of breast tissue obtained from a patient. When expressed, Id-1 gene is a prognostic indicator that breast cancer cells are invasive and metastatic, whereas Id-2 gene is a prognostic indicator that breast cancer cells are localized and noninvasive in the breast tissue.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {2008},
month = {9}
}

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