Id-1 and Id-2 genes and products as markers of epithelial cancer
Abstract
A method for detection and prognosis of breast cancer and other types of cancer. The method comprises detecting expression, if any, for both an Id-1 and an Id-2 genes, or the ratio thereof, of gene products in samples of breast tissue obtained from a patient. When expressed, Id-1 gene is a prognostic indicator that breast cancer cells are invasive and metastatic, whereas Id-2 gene is a prognostic indicator that breast cancer cells are localized and noninvasive in the breast tissue.
- Inventors:
-
- El Cerrito, CA
- Berkeley, CA
- Issue Date:
- Research Org.:
- Univ. of California (United States)
- Sponsoring Org.:
- USDOE
- OSTI Identifier:
- 984513
- Patent Number(s):
- 7429457
- Application Number:
- 09/952,534
- Assignee:
- The Regents of the University of California (Oakland, CA); California Pacific Medical Center (San Francisco, CA)
- Patent Classifications (CPCs):
-
A - HUMAN NECESSITIES A61 - MEDICAL OR VETERINARY SCIENCE A61P - SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
C - CHEMISTRY C12 - BIOCHEMISTRY C12Q - MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS
- DOE Contract Number:
- AC03-76SF00098
- Resource Type:
- Patent
- Country of Publication:
- United States
- Language:
- English
- Subject:
- 60 APPLIED LIFE SCIENCES
Citation Formats
Desprez, Pierre-Yves, and Campisi, Judith. Id-1 and Id-2 genes and products as markers of epithelial cancer. United States: N. p., 2008.
Web.
Desprez, Pierre-Yves, & Campisi, Judith. Id-1 and Id-2 genes and products as markers of epithelial cancer. United States.
Desprez, Pierre-Yves, and Campisi, Judith. Tue .
"Id-1 and Id-2 genes and products as markers of epithelial cancer". United States. https://www.osti.gov/servlets/purl/984513.
@article{osti_984513,
title = {Id-1 and Id-2 genes and products as markers of epithelial cancer},
author = {Desprez, Pierre-Yves and Campisi, Judith},
abstractNote = {A method for detection and prognosis of breast cancer and other types of cancer. The method comprises detecting expression, if any, for both an Id-1 and an Id-2 genes, or the ratio thereof, of gene products in samples of breast tissue obtained from a patient. When expressed, Id-1 gene is a prognostic indicator that breast cancer cells are invasive and metastatic, whereas Id-2 gene is a prognostic indicator that breast cancer cells are localized and noninvasive in the breast tissue.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {2008},
month = {9}
}
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