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Title: Id-1 gene and gene products as therapeutic targets for treatment of breast cancer and other types of carcinoma

A method for treatment of breast cancer and other types of cancer. The method comprises targeting and modulating Id-1 gene expression, if any, for the Id-1 gene, or gene products in breast or other epithelial cancers in a patient by delivering products that modulate Id-1 gene expression. When expressed, Id-1 gene is a prognostic indicator that cancer cells are invasive and metastatic.
Inventors:
;
Issue Date:
OSTI Identifier:
1150642
Assignee:
California Pacific Medical Center Research Institute (San Francisco, CA); The Regents of the University of California (Oakland, CA) LBNL
Patent Number(s):
8,809291
Application Number:
13/252,148
Contract Number:
AC03-765F00098
Research Org:
LBNL (Lawrence Berkeley National Laboratory (LBNL), Berkeley, CA (United States))
Sponsoring Org:
USDOE
Country of Publication:
United States
Language:
English
Subject:
60 APPLIED LIFE SCIENCES

Works referenced in this record:

Id-1 and Id-2 Are Overexpressed in Pancreatic Cancer and in Dysplastic Lesions in Chronic Pancreatitis
journal, September 1999
  • Maruyama, Haruhisa; Kleeff, Jörg; Wildi, Stefan
  • The American Journal of Pathology, Vol. 155, Issue 3, p. 815-822
  • DOI: 10.1016/S0002-9440(10)65180-2