Human AZU-1 gene, variants thereof and expressed gene products
Abstract
A human AZU-1 gene, mutants, variants and fragments thereof. Protein products encoded by the AZU-1 gene and homologs encoded by the variants of AZU-1 gene acting as tumor suppressors or markers of malignancy progression and tumorigenicity reversion. Identification, isolation and characterization of AZU-1 and AZU-2 genes localized to a tumor suppressive locus at chromosome 10q26, highly expressed in nonmalignant and premalignant cells derived from a human breast tumor progression model. A recombinant full length protein sequences encoded by the AZU-1 gene and nucleotide sequences of AZU-1 and AZU-2 genes and variant and fragments thereof. Monoclonal or polyclonal antibodies specific to AZU-1, AZU-2 encoded protein and to AZU-1, or AZU-2 encoded protein homologs.
- Inventors:
- Issue Date:
- Research Org.:
- Univ. of California, Oakland, CA (United States)
- Sponsoring Org.:
- USDOE
- OSTI Identifier:
- 1174911
- Patent Number(s):
- 6753154
- Application Number:
- 09/344,624
- Assignee:
- University Of California, The Regents Of
- Patent Classifications (CPCs):
-
C - CHEMISTRY C12 - BIOCHEMISTRY C12Q - MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS
C - CHEMISTRY C07 - ORGANIC CHEMISTRY C07K - PEPTIDES
- DOE Contract Number:
- AC03-76SF00098
- Resource Type:
- Patent
- Country of Publication:
- United States
- Language:
- English
- Subject:
- 59 BASIC BIOLOGICAL SCIENCES
Citation Formats
Chen, Huei-Mei, and Bissell, Mina. Human AZU-1 gene, variants thereof and expressed gene products. United States: N. p., 2004.
Web.
Chen, Huei-Mei, & Bissell, Mina. Human AZU-1 gene, variants thereof and expressed gene products. United States.
Chen, Huei-Mei, and Bissell, Mina. Tue .
"Human AZU-1 gene, variants thereof and expressed gene products". United States. https://www.osti.gov/servlets/purl/1174911.
@article{osti_1174911,
title = {Human AZU-1 gene, variants thereof and expressed gene products},
author = {Chen, Huei-Mei and Bissell, Mina},
abstractNote = {A human AZU-1 gene, mutants, variants and fragments thereof. Protein products encoded by the AZU-1 gene and homologs encoded by the variants of AZU-1 gene acting as tumor suppressors or markers of malignancy progression and tumorigenicity reversion. Identification, isolation and characterization of AZU-1 and AZU-2 genes localized to a tumor suppressive locus at chromosome 10q26, highly expressed in nonmalignant and premalignant cells derived from a human breast tumor progression model. A recombinant full length protein sequences encoded by the AZU-1 gene and nucleotide sequences of AZU-1 and AZU-2 genes and variant and fragments thereof. Monoclonal or polyclonal antibodies specific to AZU-1, AZU-2 encoded protein and to AZU-1, or AZU-2 encoded protein homologs.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {2004},
month = {6}
}
Works referenced in this record:
AZU-1: A Candidate Breast Tumor Suppressor and Biomarker for Tumor Progression
journal, April 2000
- Chen, Huei-Mei; Schmeichel, Karen L.; Mian, I. Saira
- Molecular Biology of the Cell, Vol. 11, Issue 4