Influenza Sensor
Abstract
A sensor for the detection of tetrameric multivalent neuraminidase within a sample is disclosed, where a positive detection indicates the presence of a target virus within the sample. Also disclosed is a trifunctional composition of matter including a trifunctional linker moiety with groups bonded thereto including (a) an alkyl chain adapted for attachment to a substrate, (b) a fluorescent moiety capable of generating a fluorescent signal, and (c) a recognition moiety having a spacer group of a defined length thereon, the recognition moiety capable of binding with tetrameric multivalent neuraminidase.
- Inventors:
-
- Los Alamos, NM
- (Los Alamos, NM)
- Issue Date:
- Research Org.:
- Los Alamos National Laboratory (LANL), Los Alamos, NM (United States)
- OSTI Identifier:
- 880869
- Patent Number(s):
- 7018792
- Application Number:
- 11/132130
- Assignee:
- The Regents of the University of California (Los Alamos, NM)
- Patent Classifications (CPCs):
-
C - CHEMISTRY C12 - BIOCHEMISTRY C12Q - MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS
G - PHYSICS G01 - MEASURING G01N - INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- DOE Contract Number:
- W-7405-ENG-36
- Resource Type:
- Patent
- Country of Publication:
- United States
- Language:
- English
Citation Formats
Swanson, Basil I, Song, Xuedong, Unkefer, Clifford, Silks, III, Louis A., and Schmidt, Jurgen G. Influenza Sensor. United States: N. p., 2006.
Web.
Swanson, Basil I, Song, Xuedong, Unkefer, Clifford, Silks, III, Louis A., & Schmidt, Jurgen G. Influenza Sensor. United States.
Swanson, Basil I, Song, Xuedong, Unkefer, Clifford, Silks, III, Louis A., and Schmidt, Jurgen G. Tue .
"Influenza Sensor". United States. https://www.osti.gov/servlets/purl/880869.
@article{osti_880869,
title = {Influenza Sensor},
author = {Swanson, Basil I and Song, Xuedong and Unkefer, Clifford and Silks, III, Louis A. and Schmidt, Jurgen G},
abstractNote = {A sensor for the detection of tetrameric multivalent neuraminidase within a sample is disclosed, where a positive detection indicates the presence of a target virus within the sample. Also disclosed is a trifunctional composition of matter including a trifunctional linker moiety with groups bonded thereto including (a) an alkyl chain adapted for attachment to a substrate, (b) a fluorescent moiety capable of generating a fluorescent signal, and (c) a recognition moiety having a spacer group of a defined length thereon, the recognition moiety capable of binding with tetrameric multivalent neuraminidase.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {Tue Mar 28 00:00:00 EST 2006},
month = {Tue Mar 28 00:00:00 EST 2006}
}