Influenza sensor
Patent
·
OSTI ID:958675
- Los Alamos, NM
A sensor for the detection of tetrameric multivalent neuraminidase within a sample is disclosed, where a positive detection indicates the presence of a target virus within the sample. Also disclosed is a trifunctional composition of matter including a trifunctional linker moiety with groups bonded thereto including (a) an alkyl chain adapted for attachment to a substrate, (b) a fluorescent moiety capable of generating a fluorescent signal, and (c) a recognition moiety having a spacer group of a defined length thereon, the recognition moiety capable of binding with tetrameric multivalent neuraminidase.
- Research Organization:
- Los Alamos National Laboratory (LANL), Los Alamos, NM (United States)
- Sponsoring Organization:
- USDOE
- DOE Contract Number:
- W-7405-ENG-36
- Assignee:
- The Regents of the University of California (Los Alamos, NM)
- Patent Number(s):
- 6,627,396
- Application Number:
- 09/699,225
- OSTI ID:
- 958675
- Country of Publication:
- United States
- Language:
- English
Guanidinobenzoic acid inhibitors of influenza virus neuraminidase 1 1Edited by R. Huber
|
journal | April 1997 |
Optical Signal Transduction Triggered by Protein−Ligand Binding: Detection of Toxins Using Multivalent Binding
|
journal | May 1998 |
Supported Membranes: Scientific and Practical Applications
|
journal | January 1996 |
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