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Title: Nucleic acid detection system and method for detecting influenza

The invention provides a rapid, sensitive and specific nucleic acid detection system which utilizes isothermal nucleic acid amplification in combination with a lateral flow chromatographic device, or DNA dipstick, for DNA-hybridization detection. The system of the invention requires no complex instrumentation or electronic hardware, and provides a low cost nucleic acid detection system suitable for highly sensitive pathogen detection. Hybridization to single-stranded DNA amplification products using the system of the invention provides a sensitive and specific means by which assays can be multiplexed for the detection of multiple target sequences.
Inventors:
;
Issue Date:
OSTI Identifier:
1172753
Assignee:
Los Alamos National Security, LLC. (Los Alamos, NM) LANL
Patent Number(s):
8,980,561
Application Number:
11/894,908
Contract Number:
AC52-06NA25396
Resource Relation:
Patent File Date: 2007 Aug 22
Research Org:
Los Alamos National Lab. (LANL), Los Alamos, NM (United States)
Sponsoring Org:
USDOE
Country of Publication:
United States
Language:
English
Subject:
59 BASIC BIOLOGICAL SCIENCES

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