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Title: Antibody-mediated reduction of .alpha.-ketoamides

Abstract

Monoclonal antibodies raised against a 4-nitrophenyl phosphonate hapten catalyze the stereospecific reduction of an .alpha.-ketoamide to the corresponding .alpha.-hydroxyamide in the presence of an appropriate reducing agent.

Inventors:
 [1];  [2]
  1. Oakland, CA
  2. East Palo Alto, CA
Issue Date:
Research Org.:
Univ. of California (United States)
OSTI Identifier:
871609
Patent Number(s):
5763249
Assignee:
Regents of University of California (Oakland, CA)
Patent Classifications (CPCs):
C - CHEMISTRY C12 - BIOCHEMISTRY C12N - MICROORGANISMS OR ENZYMES
C - CHEMISTRY C07 - ORGANIC CHEMISTRY C07K - PEPTIDES
DOE Contract Number:  
AC03-76SF00098
Resource Type:
Patent
Country of Publication:
United States
Language:
English
Subject:
antibody-mediated; reduction; alpha; -ketoamides; monoclonal; antibodies; raised; 4-nitrophenyl; phosphonate; hapten; catalyze; stereospecific; -ketoamide; corresponding; -hydroxyamide; presence; appropriate; reducing; agent; reducing agent; monoclonal antibodies; /435/530/

Citation Formats

Schultz, Peter G, and Gallop, Mark A. Antibody-mediated reduction of .alpha.-ketoamides. United States: N. p., 1998. Web.
Schultz, Peter G, & Gallop, Mark A. Antibody-mediated reduction of .alpha.-ketoamides. United States.
Schultz, Peter G, and Gallop, Mark A. Thu . "Antibody-mediated reduction of .alpha.-ketoamides". United States. https://www.osti.gov/servlets/purl/871609.
@article{osti_871609,
title = {Antibody-mediated reduction of .alpha.-ketoamides},
author = {Schultz, Peter G and Gallop, Mark A},
abstractNote = {Monoclonal antibodies raised against a 4-nitrophenyl phosphonate hapten catalyze the stereospecific reduction of an .alpha.-ketoamide to the corresponding .alpha.-hydroxyamide in the presence of an appropriate reducing agent.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {1998},
month = {1}
}

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