Antibody-mediated reduction of {alpha}-ketoamides

Title: Antibody-mediated reduction of {alpha}-ketoamides

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Abstract

Monoclonal antibodies raised against a 4-nitrophenyl phosphonate hapten catalyze the stereospecific reduction of an {alpha}-ketoamide to the corresponding {alpha}-hydroxyamide in the presence of an appropriate reducing agent.

Inventors:: Schultz, P G; Gallop, M A

Issue Date:: 1998-06-09

Research Org.:: Univ. of California (United States)

Sponsoring Org.:: USDOE, Washington, DC (United States)

OSTI Identifier:: 672571

Patent Number(s):: 5763249

Application Number:: PAN: 7-805,502

Assignee:: Univ. of California, Oakland, CA (United States)

DOE Contract Number:: AC03-76SF00098

Resource Type:: Patent

Resource Relation:: Other Information: PBD: 9 Jun 1998

Country of Publication:: United States

Language:: English

Subject:: 55 BIOLOGY AND MEDICINE, BASIC STUDIES; MONOCLONAL ANTIBODIES; ANTIGENS; REAGENTS; CATALYSTS; ANTIGEN-ANTIBODY REACTIONS

Citation Formats


                    Schultz, P G, and Gallop, M A. Antibody-mediated reduction of {alpha}-ketoamides.  United States: N. p., 1998. 
        Web.

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                    Schultz, P G, & Gallop, M A. Antibody-mediated reduction of {alpha}-ketoamides.  United States.

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                    Schultz, P G, and Gallop, M A. Tue .  
        "Antibody-mediated reduction of {alpha}-ketoamides".  United States.

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@article{osti_672571,

  title        = {Antibody-mediated reduction of {alpha}-ketoamides},

  author       = {Schultz, P G and Gallop, M A},

  abstractNote = {Monoclonal antibodies raised against a 4-nitrophenyl phosphonate hapten catalyze the stereospecific reduction of an {alpha}-ketoamide to the corresponding {alpha}-hydroxyamide in the presence of an appropriate reducing agent.},

  doi          = {},

  journal      = {},
number       = ,

  volume       = ,

  place        = {United States},

  year         = {1998},

  month        = {6}

}

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Monoclonal antibodies raised against a 4-nitrophenyl phosphonate hapten catalyze the stereospecific reduction of an .alpha.-ketoamide to the corresponding .alpha.-hydroxyamide in the presence of an appropriate reducing agent.
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