Porous membrane enabled mass spectrometry characterization of microfluidic devices
Abstract
A system for sampling a liquid includes a sample fluid conduit including a membrane having pores. The membrane prevents the passage of the sample liquid through the pores at a first pressure of the sample liquid in the sample fluid conduit. A surface sampling capture probe has a distal end. The capture probe includes a solvent supply conduit and a solvent exhaust conduit. A solvent composition flowing at the distal end of the capture probe establishes a liquid junction with the membrane and establishes a second pressure within the liquid junction at the membrane. The second pressure is lower than the first pressure. Sample liquid will be drawn through the pores of the membrane by the second pressure at the liquid junction. A method for sampling a liquid and for performing chemical analysis on a liquid are also disclosed.
- Inventors:
- Issue Date:
- Research Org.:
- Oak Ridge National Laboratory (ORNL), Oak Ridge, TN (United States)
- Sponsoring Org.:
- USDOE
- OSTI Identifier:
- 1925001
- Patent Number(s):
- 11417508
- Application Number:
- 16/744,980
- Assignee:
- UT-Battelle, LLC (Oak Ridge, TN)
- Patent Classifications (CPCs):
-
G - PHYSICS G01 - MEASURING G01N - INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
H - ELECTRICITY H01 - BASIC ELECTRIC ELEMENTS H01J - ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
- DOE Contract Number:
- AC05-00OR22725
- Resource Type:
- Patent
- Resource Relation:
- Patent File Date: 01/16/2020
- Country of Publication:
- United States
- Language:
- English
Citation Formats
Cahill, John F., Kertesz, Vilmos, and Retterer, Scott T. Porous membrane enabled mass spectrometry characterization of microfluidic devices. United States: N. p., 2022.
Web.
Cahill, John F., Kertesz, Vilmos, & Retterer, Scott T. Porous membrane enabled mass spectrometry characterization of microfluidic devices. United States.
Cahill, John F., Kertesz, Vilmos, and Retterer, Scott T. Tue .
"Porous membrane enabled mass spectrometry characterization of microfluidic devices". United States. https://www.osti.gov/servlets/purl/1925001.
@article{osti_1925001,
title = {Porous membrane enabled mass spectrometry characterization of microfluidic devices},
author = {Cahill, John F. and Kertesz, Vilmos and Retterer, Scott T.},
abstractNote = {A system for sampling a liquid includes a sample fluid conduit including a membrane having pores. The membrane prevents the passage of the sample liquid through the pores at a first pressure of the sample liquid in the sample fluid conduit. A surface sampling capture probe has a distal end. The capture probe includes a solvent supply conduit and a solvent exhaust conduit. A solvent composition flowing at the distal end of the capture probe establishes a liquid junction with the membrane and establishes a second pressure within the liquid junction at the membrane. The second pressure is lower than the first pressure. Sample liquid will be drawn through the pores of the membrane by the second pressure at the liquid junction. A method for sampling a liquid and for performing chemical analysis on a liquid are also disclosed.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {Tue Aug 16 00:00:00 EDT 2022},
month = {Tue Aug 16 00:00:00 EDT 2022}
}
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