Manipulating the circadian clock to increase gene expression
Abstract
A method of increasing gene expression by manipulating the circadian clock is described that includes transforming a photosynthetic organism to include an expression control sequence that modulates the expression of a clock gene to increase expression of a target gene. Photosynthetic organism having a modified circadian cycle reflecting this method are also described.
- Inventors:
- Issue Date:
- Research Org.:
- Vanderbilt Univ., Nashville, TN (United States); J Craig Venter Institute Inc., Rockville, MD (United States)
- Sponsoring Org.:
- USDOE
- OSTI Identifier:
- 1805531
- Patent Number(s):
- 10927365
- Application Number:
- 14/933,622
- Assignee:
- Vanderbilt University (Nashville, TN)
- Patent Classifications (CPCs):
-
C - CHEMISTRY C07 - ORGANIC CHEMISTRY C07K - PEPTIDES
C - CHEMISTRY C12 - BIOCHEMISTRY C12N - MICROORGANISMS OR ENZYMES
- DOE Contract Number:
- FG36-05GO15027
- Resource Type:
- Patent
- Resource Relation:
- Patent File Date: 11/05/2015
- Country of Publication:
- United States
- Language:
- English
Citation Formats
Johnson, Charles Hirschie, Weyman, Philip D., Xu, Qing, and Xu, Yao. Manipulating the circadian clock to increase gene expression. United States: N. p., 2021.
Web.
Johnson, Charles Hirschie, Weyman, Philip D., Xu, Qing, & Xu, Yao. Manipulating the circadian clock to increase gene expression. United States.
Johnson, Charles Hirschie, Weyman, Philip D., Xu, Qing, and Xu, Yao. Tue .
"Manipulating the circadian clock to increase gene expression". United States. https://www.osti.gov/servlets/purl/1805531.
@article{osti_1805531,
title = {Manipulating the circadian clock to increase gene expression},
author = {Johnson, Charles Hirschie and Weyman, Philip D. and Xu, Qing and Xu, Yao},
abstractNote = {A method of increasing gene expression by manipulating the circadian clock is described that includes transforming a photosynthetic organism to include an expression control sequence that modulates the expression of a clock gene to increase expression of a target gene. Photosynthetic organism having a modified circadian cycle reflecting this method are also described.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {Tue Feb 23 00:00:00 EST 2021},
month = {Tue Feb 23 00:00:00 EST 2021}
}
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