skip to main content
DOE Patents title logo U.S. Department of Energy
Office of Scientific and Technical Information

Title: Production of isotopes using high power proton beams

Abstract

The invention provides for a method for producing isotopes using a beam of particles from an accelerator, whereby the beam is maintained at between about 70 to 2000 MeV; and contacting a thorium-containing target with the particles. The medically important isotope .sup.225Ac is produced via the nuclear reaction (p,2p6n), whereby an energetic proton causes the ejection of 2 protons and 6 neutrons from a .sup.232Th target nucleus. Another medically important isotope .sup.213Bi is then available as a decay product. The production of highly purified .sup.211At is also provided.

Inventors:
;
Issue Date:
Research Org.:
Argonne National Lab. (ANL), Argonne, IL (United States)
Sponsoring Org.:
USDOE
OSTI Identifier:
1568155
Patent Number(s):
10,249,399
Application Number:
14/949,665
Assignee:
UChicago Argonne, LLC (Chicago, IL)
DOE Contract Number:  
AC02-06CH11357
Resource Type:
Patent
Resource Relation:
Patent File Date: 11/23/2015
Country of Publication:
United States
Language:
English

Citation Formats

Nolen, Jr., Jerry A., and Gomes, Itacil C. Production of isotopes using high power proton beams. United States: N. p., 2019. Web.
Nolen, Jr., Jerry A., & Gomes, Itacil C. Production of isotopes using high power proton beams. United States.
Nolen, Jr., Jerry A., and Gomes, Itacil C. Tue . "Production of isotopes using high power proton beams". United States. https://www.osti.gov/servlets/purl/1568155.
@article{osti_1568155,
title = {Production of isotopes using high power proton beams},
author = {Nolen, Jr., Jerry A. and Gomes, Itacil C.},
abstractNote = {The invention provides for a method for producing isotopes using a beam of particles from an accelerator, whereby the beam is maintained at between about 70 to 2000 MeV; and contacting a thorium-containing target with the particles. The medically important isotope .sup.225Ac is produced via the nuclear reaction (p,2p6n), whereby an energetic proton causes the ejection of 2 protons and 6 neutrons from a .sup.232Th target nucleus. Another medically important isotope .sup.213Bi is then available as a decay product. The production of highly purified .sup.211At is also provided.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {2019},
month = {4}
}

Patent:

Save / Share:

Works referenced in this record:

Actinium-225 complexes and conjugates for targeted radiotherapy
patent, December 2003


Process for producing astatine-211 for radiopharmaceutical use
patent, July 1987


Transmutable radiotherapy device
patent, September 2001


Spallation device for producing neutrons
patent, May 2005


Actinium radioisotope products of enhanced purity
patent, June 2010


Method for producing Ac-225 by irradiation of Ra-226 with protons
patent, October 2001


Radiotherapy
patent, June 2006


Process and apparatus for the production of BI-213 cations
patent, December 1998


Method of producing Actinium-225 and daughters
patent, January 2004


Method for producing actinium-225 and bismuth-213
patent, October 1994