High temperature and high beam current compatible targets and methods thereof for generating noble gas/radiohalogen generators for medical isotopes
Abstract
A method of providing alpha particle emitters and materials suitable for use in generating the alpha particles for medical treatment is disclosed. Metal oxide targets, preferentially Bi2O3 pellets and Bi2O3 coatings on metallic or metal oxide substrates are formed. The targets placed in a heated vacuum chamber subjecting to irradiation using a 6Li beam at an elevated temperature below the melting point of the target generate a radioactive gas, such as 211Rn, the radioactive gas is carried by an inert gas which is delivered a carrier for, such as a carbon column or oil for delivery to a treatment facility. The radioactive gas such as 211Rn generates 211At, which has a useable half-life of at least about 14 hours, in turn releases alpha particles which are effective for use in medical procedures.
- Inventors:
- Issue Date:
- Research Org.:
- Innosense LLC, Torrance, CA (United States)
- Sponsoring Org.:
- USDOE Office of Science (SC)
- OSTI Identifier:
- 2293674
- Patent Number(s):
- 11776705
- Application Number:
- 17/151,147
- Assignee:
- Innosense LLC (Torrance, CA)
- DOE Contract Number:
- SC0007572; SC0019587
- Resource Type:
- Patent
- Resource Relation:
- Patent File Date: 01/16/2021
- Country of Publication:
- United States
- Language:
- English
Citation Formats
Sampathkumaran, Uma, Winter, Raymond, and Madakashira, Harini. High temperature and high beam current compatible targets and methods thereof for generating noble gas/radiohalogen generators for medical isotopes. United States: N. p., 2023.
Web.
Sampathkumaran, Uma, Winter, Raymond, & Madakashira, Harini. High temperature and high beam current compatible targets and methods thereof for generating noble gas/radiohalogen generators for medical isotopes. United States.
Sampathkumaran, Uma, Winter, Raymond, and Madakashira, Harini. Tue .
"High temperature and high beam current compatible targets and methods thereof for generating noble gas/radiohalogen generators for medical isotopes". United States. https://www.osti.gov/servlets/purl/2293674.
@article{osti_2293674,
title = {High temperature and high beam current compatible targets and methods thereof for generating noble gas/radiohalogen generators for medical isotopes},
author = {Sampathkumaran, Uma and Winter, Raymond and Madakashira, Harini},
abstractNote = {A method of providing alpha particle emitters and materials suitable for use in generating the alpha particles for medical treatment is disclosed. Metal oxide targets, preferentially Bi2O3 pellets and Bi2O3 coatings on metallic or metal oxide substrates are formed. The targets placed in a heated vacuum chamber subjecting to irradiation using a 6Li beam at an elevated temperature below the melting point of the target generate a radioactive gas, such as 211Rn, the radioactive gas is carried by an inert gas which is delivered a carrier for, such as a carbon column or oil for delivery to a treatment facility. The radioactive gas such as 211Rn generates 211At, which has a useable half-life of at least about 14 hours, in turn releases alpha particles which are effective for use in medical procedures.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {Tue Oct 03 00:00:00 EDT 2023},
month = {Tue Oct 03 00:00:00 EDT 2023}
}
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