Production of isotopes using high power proton beams
Abstract
The invention provides for a method for producing isotopes using a beam of particles from an accelerator, whereby the beam is maintained at between about 70 to 2000 MeV; and contacting a thorium-containing target with the particles. The medically important isotope .sup.225Ac is produced via the nuclear reaction (p,2p6n), whereby an energetic proton causes the ejection of 2 protons and 6 neutrons from a .sup.232Th target nucleus. Another medically important isotope .sup.213Bi is then available as a decay product. The production of highly purified .sup.211At is also provided.
- Inventors:
- Issue Date:
- Research Org.:
- Argonne National Lab. (ANL), Argonne, IL (United States)
- Sponsoring Org.:
- USDOE
- OSTI Identifier:
- 1345367
- Patent Number(s):
- 9,202,602
- Application Number:
- 13/025,079
- Assignee:
- UCHICAGO ARGONNE, LLC (Chicago, IL)
- DOE Contract Number:
- AC02-06CH11357
- Resource Type:
- Patent
- Resource Relation:
- Patent File Date: 2011 Feb 10
- Country of Publication:
- United States
- Language:
- English
- Subject:
- 43 PARTICLE ACCELERATORS
Citation Formats
Nolen, Jr., Jerry A., and Gomes, Itacil C. Production of isotopes using high power proton beams. United States: N. p., 2015.
Web.
Nolen, Jr., Jerry A., & Gomes, Itacil C. Production of isotopes using high power proton beams. United States.
Nolen, Jr., Jerry A., and Gomes, Itacil C. Tue .
"Production of isotopes using high power proton beams". United States. https://www.osti.gov/servlets/purl/1345367.
@article{osti_1345367,
title = {Production of isotopes using high power proton beams},
author = {Nolen, Jr., Jerry A. and Gomes, Itacil C.},
abstractNote = {The invention provides for a method for producing isotopes using a beam of particles from an accelerator, whereby the beam is maintained at between about 70 to 2000 MeV; and contacting a thorium-containing target with the particles. The medically important isotope .sup.225Ac is produced via the nuclear reaction (p,2p6n), whereby an energetic proton causes the ejection of 2 protons and 6 neutrons from a .sup.232Th target nucleus. Another medically important isotope .sup.213Bi is then available as a decay product. The production of highly purified .sup.211At is also provided.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {2015},
month = {12}
}
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Works referenced in this record:
Spallation of Uranium and Thorium Nuclei with Bev-Energy Protons
journal, July 1961
- Pate, B. D.; Poskanzer, A. M.
- Physical Review, Vol. 123, Issue 2
Production of 225Ac and 223Ra by irradiation of Th with accelerated protons
journal, February 2011
- Zhuikov, B. L.; Kalmykov, S. N.; Ermolaev, S. V.
- Radiochemistry, Vol. 53, Issue 1, p. 73-80
Production of Ac-225 from Th-229 for Targeted α Therapy
journal, October 2005
- Apostolidis, C.; Molinet, R.; Rasmussen, G.
- Analytical Chemistry, Vol. 77, Issue 19
Targeted Killing of Virally Infected Cells by Radiolabeled Antibodies to Viral Proteins
journal, November 2006
- Dadachova, Ekaterina; Patel, Mahesh C.; Toussi, Sima
- PLoS Medicine, Vol. 3, Issue 11
Targeted α-particle radiotherapy with 211At-labeled monoclonal antibodies
journal, October 2007
- Zalutsky, Michael R.; Reardon, David A.; Pozzi, Oscar R.
- Nuclear Medicine and Biology, Vol. 34, Issue 7, p. 779-785
Cancer Therapy with Alpha-Emitters Labeled Peptides
journal, May 2010
- Dadachova, Ekaterina
- Seminars in Nuclear Medicine, Vol. 40, Issue 3