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Title: Production of isotopes using high power proton beams

The invention provides for a method for producing isotopes using a beam of particles from an accelerator, whereby the beam is maintained at between about 70 to 2000 MeV; and contacting a thorium-containing target with the particles. The medically important isotope .sup.225Ac is produced via the nuclear reaction (p,2p6n), whereby an energetic proton causes the ejection of 2 protons and 6 neutrons from a .sup.232Th target nucleus. Another medically important isotope .sup.213Bi is then available as a decay product. The production of highly purified .sup.211At is also provided.
Inventors:
;
Issue Date:
OSTI Identifier:
1345367
Assignee:
UCHICAGO ARGONNE, LLC (Chicago, IL) ANL
Patent Number(s):
9,202,602
Application Number:
13/025,079
Contract Number:
AC02-06CH11357
Resource Relation:
Patent File Date: 2011 Feb 10
Research Org:
Argonne National Lab. (ANL), Argonne, IL (United States)
Sponsoring Org:
USDOE
Country of Publication:
United States
Language:
English
Subject:
43 PARTICLE ACCELERATORS

Works referenced in this record:

Production of 225Ac and 223Ra by irradiation of Th with accelerated protons
journal, February 2011

Targeted α-particle radiotherapy with 211At-labeled monoclonal antibodies
journal, October 2007