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Title: De novo design of allosteric proteins

Abstract

Methods and compositions for making and isolating allosteric DNA binding proteins that bind to one or more allosteric effectors to induce a conformation change in the proteins are provided.

Inventors:
; ;
Issue Date:
Research Org.:
Harvard Univ., Cambridge, MA (United States)
Sponsoring Org.:
USDOE
OSTI Identifier:
1469336
Patent Number(s):
10041065
Application Number:
15/628,690
Assignee:
President and Fellows of Harvard College (Cambridge, MA)
Patent Classifications (CPCs):
G - PHYSICS G16 - INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS G16B - BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
G - PHYSICS G01 - MEASURING G01N - INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
DOE Contract Number:  
FG02-02ER63445
Resource Type:
Patent
Resource Relation:
Patent File Date: 2017 Jun 21
Country of Publication:
United States
Language:
English
Subject:
59 BASIC BIOLOGICAL SCIENCES

Citation Formats

Raman, Srivatsan, Taylor, Noah D., and Church, George M. De novo design of allosteric proteins. United States: N. p., 2018. Web.
Raman, Srivatsan, Taylor, Noah D., & Church, George M. De novo design of allosteric proteins. United States.
Raman, Srivatsan, Taylor, Noah D., and Church, George M. Tue . "De novo design of allosteric proteins". United States. https://www.osti.gov/servlets/purl/1469336.
@article{osti_1469336,
title = {De novo design of allosteric proteins},
author = {Raman, Srivatsan and Taylor, Noah D. and Church, George M.},
abstractNote = {Methods and compositions for making and isolating allosteric DNA binding proteins that bind to one or more allosteric effectors to induce a conformation change in the proteins are provided.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {2018},
month = {8}
}

Patent:

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