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Title: De novo design of allosteric proteins

Methods and compositions for making and isolating allosteric DNA binding proteins that bind to one or more allosteric effectors to induce a conformation change in the proteins are provided.
Inventors:
; ;
Issue Date:
OSTI Identifier:
1469336
Assignee:
President and Fellows of Harvard College (Cambridge, MA) CHO
Patent Number(s):
10,041,065
Application Number:
15/628,690
Contract Number:
FG02-02ER63445
Resource Relation:
Patent File Date: 2017 Jun 21
Research Org:
President and Fellows of Harvard College, Cambridge, MA (United States)
Sponsoring Org:
USDOE
Country of Publication:
United States
Language:
English
Subject:
59 BASIC BIOLOGICAL SCIENCES