De novo design of allosteric proteins
Abstract
Methods and compositions for making and isolating allosteric DNA binding proteins that bind to one or more allosteric effectors to induce a conformation change in the proteins are provided.
- Inventors:
- Issue Date:
- Research Org.:
- Harvard Univ., Cambridge, MA (United States)
- Sponsoring Org.:
- USDOE
- OSTI Identifier:
- 1469336
- Patent Number(s):
- 10041065
- Application Number:
- 15/628,690
- Assignee:
- President and Fellows of Harvard College (Cambridge, MA)
- Patent Classifications (CPCs):
-
C - CHEMISTRY C07 - ORGANIC CHEMISTRY C07K - PEPTIDES
C - CHEMISTRY C12 - BIOCHEMISTRY C12N - MICROORGANISMS OR ENZYMES
- DOE Contract Number:
- FG02-02ER63445
- Resource Type:
- Patent
- Resource Relation:
- Patent File Date: 2017 Jun 21
- Country of Publication:
- United States
- Language:
- English
- Subject:
- 59 BASIC BIOLOGICAL SCIENCES
Citation Formats
Raman, Srivatsan, Taylor, Noah D., and Church, George M. De novo design of allosteric proteins. United States: N. p., 2018.
Web.
Raman, Srivatsan, Taylor, Noah D., & Church, George M. De novo design of allosteric proteins. United States.
Raman, Srivatsan, Taylor, Noah D., and Church, George M. Tue .
"De novo design of allosteric proteins". United States. https://www.osti.gov/servlets/purl/1469336.
@article{osti_1469336,
title = {De novo design of allosteric proteins},
author = {Raman, Srivatsan and Taylor, Noah D. and Church, George M.},
abstractNote = {Methods and compositions for making and isolating allosteric DNA binding proteins that bind to one or more allosteric effectors to induce a conformation change in the proteins are provided.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {2018},
month = {8}
}
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De novo design of allosteric proteins
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- Raman, Srivatsan; Taylor, Noah D.; Church, George M.
- US Patent Document 9,721,061