De novo design of allosteric proteins
Abstract
Methods and compositions for making and isolating allosteric DNA binding proteins that bind to one or more allosteric effectors to induce a conformation change in the proteins are provided.
- Inventors:
- Issue Date:
- Research Org.:
- Harvard Univ., Cambridge, MA (United States)
- Sponsoring Org.:
- USDOE
- OSTI Identifier:
- 1568741
- Patent Number(s):
- 10385333
- Application Number:
- 16/039,917
- Assignee:
- President and Fellows of Harvard College (Cambridge, MA)
- Patent Classifications (CPCs):
-
G - PHYSICS G16 - INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS G16B - BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
G - PHYSICS G01 - MEASURING G01N - INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- DOE Contract Number:
- FG02-02ER63445
- Resource Type:
- Patent
- Resource Relation:
- Patent File Date: 07/19/2018
- Country of Publication:
- United States
- Language:
- English
Citation Formats
Raman, Srivatsan, Taylor, Noah D., and Church, George M. De novo design of allosteric proteins. United States: N. p., 2019.
Web.
Raman, Srivatsan, Taylor, Noah D., & Church, George M. De novo design of allosteric proteins. United States.
Raman, Srivatsan, Taylor, Noah D., and Church, George M. Tue .
"De novo design of allosteric proteins". United States. https://www.osti.gov/servlets/purl/1568741.
@article{osti_1568741,
title = {De novo design of allosteric proteins},
author = {Raman, Srivatsan and Taylor, Noah D. and Church, George M.},
abstractNote = {Methods and compositions for making and isolating allosteric DNA binding proteins that bind to one or more allosteric effectors to induce a conformation change in the proteins are provided.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {2019},
month = {8}
}
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