Beta-alanine/alpha-ketoglutarate aminotransferase for 3-hydroxypropionic acid production
Abstract
The present disclosure provides novel beta-alanine/alpha ketoglutarate aminotransferase nucleic acid and protein sequences having increased biological activity. Also provided are cells containing such enzymes, as well as methods of their use, for example to produce malonyl semialdehyde and downstream products thereof, such as 3-hydroxypropionic acid and derivatives thereof.
- Inventors:
- Issue Date:
- Research Org.:
- Cargill, Incorporated, Wayzata, MN (United States)
- Sponsoring Org.:
- USDOE
- OSTI Identifier:
- 1164042
- Patent Number(s):
- 8889391
- Application Number:
- 13/230,217
- Assignee:
- Cargill, Incorporated (Wayzata, MN)
- Patent Classifications (CPCs):
-
C - CHEMISTRY C12 - BIOCHEMISTRY C12N - MICROORGANISMS OR ENZYMES
C - CHEMISTRY C12 - BIOCHEMISTRY C12P - FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE {
- Resource Type:
- Patent
- Country of Publication:
- United States
- Language:
- English
- Subject:
- 59 BASIC BIOLOGICAL SCIENCES; 60 APPLIED LIFE SCIENCES; 37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CHEMISTRY
Citation Formats
Jessen, Holly Jean, Liao, Hans H, Gort, Steven John, and Selifonova, Olga V. Beta-alanine/alpha-ketoglutarate aminotransferase for 3-hydroxypropionic acid production. United States: N. p., 2014.
Web.
Jessen, Holly Jean, Liao, Hans H, Gort, Steven John, & Selifonova, Olga V. Beta-alanine/alpha-ketoglutarate aminotransferase for 3-hydroxypropionic acid production. United States.
Jessen, Holly Jean, Liao, Hans H, Gort, Steven John, and Selifonova, Olga V. Tue .
"Beta-alanine/alpha-ketoglutarate aminotransferase for 3-hydroxypropionic acid production". United States. https://www.osti.gov/servlets/purl/1164042.
@article{osti_1164042,
title = {Beta-alanine/alpha-ketoglutarate aminotransferase for 3-hydroxypropionic acid production},
author = {Jessen, Holly Jean and Liao, Hans H and Gort, Steven John and Selifonova, Olga V},
abstractNote = {The present disclosure provides novel beta-alanine/alpha ketoglutarate aminotransferase nucleic acid and protein sequences having increased biological activity. Also provided are cells containing such enzymes, as well as methods of their use, for example to produce malonyl semialdehyde and downstream products thereof, such as 3-hydroxypropionic acid and derivatives thereof.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {2014},
month = {11}
}
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