Human Host Cellular Response to HCoV-229E Infection Transcriptomics (ACS-DP1)

doi:10.25584/PPI/2467508

Title: Human Host Cellular Response to HCoV-229E Infection Transcriptomics (ACS-DP1)

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Abstract

The purpose of this experiment was to evaluate the human host cellular response to wild-type Human coronavirus strain 229E (HCoV-229E) infection. Sample data was obtained for mock and infected immortalized human lung epithelial cells (A549) (MOI 5), immortalized human lung fibroblasts cells (MRC5) (MOI5), and primary human airway epithelial (HAE) (MOI 3) cells from lung tissue. Sample data was acquired using an Illumina HiSeq 2000 sequencer system and processed for RNA sequencing (RNA-Seq) expression analysis.

Publication Date:: Tue Sep 24 20:00:00 EDT 2024

DOE Contract Number:: AC05-76RL01830

Research Org.:: Pacific Northwest National Laboratory (PNNL), Richland, WA (United States)

Sponsoring Org.:: SC

Collaborations:: Predictive Phenomics Initiative, Pacific Northwest National Laboratory

Subject:: 59 BASIC BIOLOGICAL SCIENCES; HCov-229E; Homo sapiens; Lethal Human Viruses; Predictive Phenomics; RNA-Seq; Transcriptomics

OSTI Identifier:: 2467508

DOI:: https://doi.org/10.25584/PPI/2467508

Citation Formats


                    Human Host Cellular Response to HCoV-229E Infection Transcriptomics (ACS-DP1).  United States: N. p., 2024. 
        Web.  doi:10.25584/PPI/2467508.

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                    Human Host Cellular Response to HCoV-229E Infection Transcriptomics (ACS-DP1).  United States.  doi:https://doi.org/10.25584/PPI/2467508

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                    2024.  
"Human Host Cellular Response to HCoV-229E Infection Transcriptomics (ACS-DP1)".  United States.  doi:https://doi.org/10.25584/PPI/2467508.  https://www.osti.gov/servlets/purl/2467508. Pub date:Tue Sep 24 20:00:00 EDT 2024

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@article{osti_2467508,

  title        = {Human Host Cellular Response to HCoV-229E Infection Transcriptomics (ACS-DP1)},

  
  abstractNote = {The purpose of this experiment was to evaluate the human host cellular response to wild-type Human coronavirus strain 229E (HCoV-229E) infection. Sample data was obtained for mock and infected immortalized human lung epithelial cells (A549) (MOI 5), immortalized human lung fibroblasts cells (MRC5) (MOI5), and primary human airway epithelial (HAE) (MOI 3) cells from lung tissue. Sample data was acquired using an Illumina HiSeq 2000 sequencer system and processed for RNA sequencing (RNA-Seq) expression analysis.},

  doi          = {10.25584/PPI/2467508},

  journal      = {},

  number       = ,

  volume       = ,

  place        = {United States},

  year         = {Tue Sep 24 20:00:00 EDT 2024},

  month        = {Tue Sep 24 20:00:00 EDT 2024}

}

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DOI: https://doi.org/10.25584/PPI/2467508

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