Y chromosome specific nucleic acid probe and method for determining the Y chromosome in situ

Gray, Joe W; Weier, Heinz-Ulrich

Title: Y chromosome specific nucleic acid probe and method for determining the Y chromosome in situ

Patent · Thu Jan 01 00:00:00 EST 1998

OSTI ID:871992

Gray, Joe W ^[1]; Weier, Heinz-Ulrich ^[2]

Livermore, CA
Tracy, CA

A method for producing a Y chromosome specific probe selected from highly repeating sequences on that chromosome is described. There is little or no nonspecific binding to autosomal and X chromosomes, and a very large signal is provided. Inventive primers allowing the use of PCR for both sample amplification and probe production are described, as is their use in producing large DNA chromosome painting sequences.

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Research Organization:: Lawrence Livermore National Laboratory (LLNL), Livermore, CA (United States)

DOE Contract Number:: W-7405-ENG-48

Assignee:: Regents of University of California (Alameda, CA)

Patent Number(s):: US 5840482

OSTI ID:: 871992

Country of Publication:: United States

Language:: English

References (24)

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Title: Y chromosome specific nucleic acid probe and method for determining the Y chromosome in situ

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References (24)

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