Reimmigration of bone marrow stem cells in mice in roentgen experiments
Journal Article
·
· Dokl. Biol. Sci. (Engl. Transl.); (United States)
OSTI ID:7361402
One or four extremities of mice were exposed to x radiation in a dose of 2000 R, inactivating the bone marrow. Immediately, one, or three hrs. afterwards the bodies of the mice were exposed to 720R radiation while the previously irradiated portions were shielded with lead. Observations were made on survival, spleen colony formation nine days after irradiation and weight changes of the spleen after one month. The survival rate of the animals indicated that the irradiated bone marrow of the extremities was colonized by migration of unexposed cells to irradiated bone marrow. Data on spleen colony formation and recovery of its weight served as evidence for repopulation of hemopoietic tissue in cases where one or four previously irradiated extremities were shielded with an interval of three hrs. between exposures. (HLW)
- Research Organization:
- Central Roentgen-Radiological Research Inst., Leningrad
- OSTI ID:
- 7361402
- Journal Information:
- Dokl. Biol. Sci. (Engl. Transl.); (United States), Journal Name: Dokl. Biol. Sci. (Engl. Transl.); (United States) Vol. 223:1/6; ISSN DKBSA
- Country of Publication:
- United States
- Language:
- English
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Related Subjects
560152* -- Radiation Effects on Animals-- Animals
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ANIMAL CELLS
ANIMALS
BIOLOGICAL EFFECTS
BIOLOGICAL RADIATION EFFECTS
BIOLOGICAL RECOVERY
BIOLOGICAL REGENERATION
BODY
BONE MARROW
CFU
ELECTROMAGNETIC RADIATION
HEMATOPOIETIC SYSTEM
IONIZING RADIATIONS
MAMMALS
MICE
ORGANS
RADIATION EFFECTS
RADIATIONS
RECOVERY
RODENTS
SHIELDING
SOMATIC CELLS
SPLEEN
STEM CELLS
SURVIVAL TIME
TISSUES
VERTEBRATES
WEIGHT
X RADIATION
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ANIMAL CELLS
ANIMALS
BIOLOGICAL EFFECTS
BIOLOGICAL RADIATION EFFECTS
BIOLOGICAL RECOVERY
BIOLOGICAL REGENERATION
BODY
BONE MARROW
CFU
ELECTROMAGNETIC RADIATION
HEMATOPOIETIC SYSTEM
IONIZING RADIATIONS
MAMMALS
MICE
ORGANS
RADIATION EFFECTS
RADIATIONS
RECOVERY
RODENTS
SHIELDING
SOMATIC CELLS
SPLEEN
STEM CELLS
SURVIVAL TIME
TISSUES
VERTEBRATES
WEIGHT
X RADIATION