Postradiation migration of polypotent hemopoietic stem cells from shielded bone marrow of mice following hemorrhage and transfusion of syngenic erythrocytes
Conference
·
· Radiobiology (USSR) (Engl. Transl.); (United States)
OSTI ID:5339864
Mice were exposed to a lethal dose of radiation with the hind limb shielded and blood was removed from the orbital sinus to produce hemorrhage. Intravenous injections of erythrocytes were given before irradiation. The animals were killed 8 days after irradiation and the number of spleen colonies of hemopoietic cells was counted. Results indicated that hemorrhage stimulated and erythrocyte transfusions inhibited migration of polypotent hemopoietic cells from bone marrow to the spleen. (HLW)
- Research Organization:
- Inst. of Clinical and Experimental Medicine, Novosibirsk, USSR
- OSTI ID:
- 5339864
- Journal Information:
- Radiobiology (USSR) (Engl. Transl.); (United States), Journal Name: Radiobiology (USSR) (Engl. Transl.); (United States) Vol. 17:2; ISSN RADBA
- Country of Publication:
- United States
- Language:
- English
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Related Subjects
560152* -- Radiation Effects on Animals-- Animals
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ANIMAL CELLS
ANIMALS
BIOLOGICAL EFFECTS
BIOLOGICAL MATERIALS
BIOLOGICAL RADIATION EFFECTS
BLOOD
BLOOD CELLS
BODY
BODY FLUIDS
BONE MARROW
CFU
DISEASES
ERYTHROCYTES
HEMATOPOIETIC SYSTEM
HEMORRHAGE
MAMMALS
MICE
MIGRATION
ORGANS
PATHOLOGICAL CHANGES
RADIATION EFFECTS
RODENTS
SOMATIC CELLS
SPLEEN
STEM CELLS
SYMPTOMS
THERAPY
TISSUES
TRANSFUSIONS
VERTEBRATES
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ANIMAL CELLS
ANIMALS
BIOLOGICAL EFFECTS
BIOLOGICAL MATERIALS
BIOLOGICAL RADIATION EFFECTS
BLOOD
BLOOD CELLS
BODY
BODY FLUIDS
BONE MARROW
CFU
DISEASES
ERYTHROCYTES
HEMATOPOIETIC SYSTEM
HEMORRHAGE
MAMMALS
MICE
MIGRATION
ORGANS
PATHOLOGICAL CHANGES
RADIATION EFFECTS
RODENTS
SOMATIC CELLS
SPLEEN
STEM CELLS
SYMPTOMS
THERAPY
TISSUES
TRANSFUSIONS
VERTEBRATES