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Remigration of mouse bone marrow stem cells

Journal Article · · Radiobiology (USSR) (Engl. Transl.); (United States)
OSTI ID:5518835
;
It was demonstrated on mice that bone marrow stem cells migrate to the irradiated (2000 R) region of bone marrow, then migrate again (remigrate) to the rest of the body after irradiation thereof, with shielding of previously irradiated regions, repopulating hemopoietic organs. The data on survival of animals, cellularity of bone marrow, weight of the spleen and endogenous colony formation in it are indicative of remigration. The effectiveness of remigration depends on the size of the initially irrated bone marrow region shielded for the second irradiation, as well as interval between irradiations Remigration is manifested by a decrease in number of myelokaryocytes in the region from which it occurs, in accordance with repopulation of the rest of the bone marrow.
Research Organization:
Central Scientific Research Inst. of Roentgenology and Radiology, Leningrad, USSR
OSTI ID:
5518835
Journal Information:
Radiobiology (USSR) (Engl. Transl.); (United States), Journal Name: Radiobiology (USSR) (Engl. Transl.); (United States) Vol. 19:3; ISSN RADBA
Country of Publication:
United States
Language:
English

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Related Subjects

560152* -- Radiation Effects on Animals-- Animals
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ANIMAL CELLS
ANIMALS
BIOLOGICAL EFFECTS
BIOLOGICAL LOCALIZATION
BIOLOGICAL RADIATION EFFECTS
BODY
BONE MARROW
COLONY FORMATION
ELECTROMAGNETIC RADIATION
EXTERNAL IRRADIATION
HEMATOPOIETIC SYSTEM
IONIZING RADIATIONS
IRRADIATION
MAMMALS
MICE
ORGANS
PARTIAL BODY IRRADIATION
RADIATION EFFECTS
RADIATIONS
RODENTS
SOMATIC CELLS
SPLEEN
SPLEEN COLONY FORMATION
STEM CELLS
SURVIVAL CURVES
TISSUES
VERTEBRATES
WHOLE-BODY IRRADIATION
X RADIATION