Morphology of the early stages of recovery of hemopoiesis in the spleen of irradiated mice after bone marrow transplantation. [Gamma radiation]
Journal Article
·
· Dokl. Biol. Sci. (Engl. Transl.); (United States)
OSTI ID:7354750
Mice were given a single whole-body dose of 750 R of gamma radiation and 24 h later syngeneic bone marrow was injected intravenously. At intervals up to 6 days the mice were killed and the cell composition of the spleen was studied. Three stages of restoration of hematopoiesis in the spleen were observed: a generalized stimulation of reticular cells of the recipients' splenic red pulp; formation of microcolonies of undifferentiated blast cells; and the appearance of hematologically differential cells and proliferation of colony-forming units. (HLW)
- Research Organization:
- Military Medical Academy, Leningrad
- OSTI ID:
- 7354750
- Journal Information:
- Dokl. Biol. Sci. (Engl. Transl.); (United States), Journal Name: Dokl. Biol. Sci. (Engl. Transl.); (United States) Vol. 225:1-6; ISSN DKBSA
- Country of Publication:
- United States
- Language:
- English
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Related Subjects
560152* -- Radiation Effects on Animals-- Animals
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ANIMAL CELLS
ANIMALS
BIOLOGICAL EFFECTS
BIOLOGICAL RADIATION EFFECTS
BIOLOGICAL RECOVERY
BLOOD FORMATION
BODY
BONE MARROW
CELL PROLIFERATION
CFU
ELECTROMAGNETIC RADIATION
GAMMA RADIATION
HEMATOPOIETIC SYSTEM
IONIZING RADIATIONS
MAMMALS
MICE
ORGANS
RADIATION EFFECTS
RADIATIONS
RECOVERY
RODENTS
SOMATIC CELLS
SPLEEN
SPLEEN CELLS
TISSUES
TRANSPLANTS
VERTEBRATES
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ANIMAL CELLS
ANIMALS
BIOLOGICAL EFFECTS
BIOLOGICAL RADIATION EFFECTS
BIOLOGICAL RECOVERY
BLOOD FORMATION
BODY
BONE MARROW
CELL PROLIFERATION
CFU
ELECTROMAGNETIC RADIATION
GAMMA RADIATION
HEMATOPOIETIC SYSTEM
IONIZING RADIATIONS
MAMMALS
MICE
ORGANS
RADIATION EFFECTS
RADIATIONS
RECOVERY
RODENTS
SOMATIC CELLS
SPLEEN
SPLEEN CELLS
TISSUES
TRANSPLANTS
VERTEBRATES