Detection limits of chemical spot tests toward certain carcinogens on metal, painted, and conrete surfaces
The formation of chromogenic and fluorogenic derivatives of certain aromatic amines designated by the Occupational Safety and Health Administration as cancer-suspect agents has allowed these compounds to be detected at very low levels through chemical spot tests. Well-defined painted, metal, and concrete were used as standard surfaces to evaluate the limit of detection values of these compounds as a function of both the visualization reagent and the method of detection. The chromogenic reagent of choice was Ehrlich's reagent and the fluorogenic reagents were either fluorescamine or o-phthalaldehyde. The limit of detection values for these compounds in terms of grams of analyte per cm/sup 2/ of surface being analyzed ranged from the low nanogram to 5-..mu..g level depending upon the compound, sampling technique, and surface involved. The combination of sampling technique and visualization reagent employed extend the limit of detection to levels considerably lower than previously reported.
- Research Organization:
- Los Alamos Scientific Lab., NM
- OSTI ID:
- 7319658
- Journal Information:
- Anal. Chem.; (United States), Journal Name: Anal. Chem.; (United States) Vol. 48:14; ISSN ANCHA
- Country of Publication:
- United States
- Language:
- English
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63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
BUILDING MATERIALS
CARCINOGENS
CHEMICAL ANALYSIS
COATINGS
CONCRETES
ELEMENTS
MATERIALS
METALS
PAINTS
SURFACES