Skip to main content
U.S. Department of Energy
Office of Scientific and Technical Information

Demonstration of the oncogenic potential of Herpes simplex viruses and human cytomegalovirus. [UV radiation]

Journal Article · · Cold Spring Harbor Symp. Quant. Biol.; (United States)
OSTI ID:7261947

The following topics are reviewed: transformation of hamster embryo cells by herpes simplex viruses and human cytomegalovirus; the use of uv radiation and photodynamic action to inactivate virus infectivity while retaining the transformation potential of the virus; detection of virus-specific antigens in transformed cells; oncogenicity of HSV- and CMV-transformed cells in vivo; immunological studies of metastases induced by herpes virus-transformed cells; resistance of transformed cells to superinfection; maintenance of the virus genome in the transformed state; and stimulation of cellular DNA synthesis by human cytomegalovirus. (HLW)

Research Organization:
Pennsylvania State Univ., Hershey
OSTI ID:
7261947
Journal Information:
Cold Spring Harbor Symp. Quant. Biol.; (United States), Journal Name: Cold Spring Harbor Symp. Quant. Biol.; (United States) Vol. 39:8; ISSN CSHSA
Country of Publication:
United States
Language:
English