Radioimmunoassay of serum alpha-fetoprotein in patients with different malignant tumors. [/sup 125/I tracer technique]

Journal Article · Thu Jul 01 04:00:00 EDT 1976 · Cancer; (United States)

OSTI ID:7181919

Lie-Injo, Luan Eng; Caldwell, J; Ganesan, S; Ganesan, J

The level of serum alpha-fetoprotein (AFP) was estimated by radioimmunoassay in 153 normal healthy Malaysians of different ethnic groups. The mean level was 7.5 InU/ml (SD 2.28 InU/ml). Among 330 patients with malignant tumors, 11 had increased levels of AFP. The only patient who had hepatoma had a very high level of serum AFP. High levels were also found in three of four patients with dysgerminoma of the ovary, in the only two patients with carcinoma of the testis, and in one patient with secondary carcinoma of the humerus of unknown origin. Lower, but significantly increased levels were observed in one patient (of 48) with breast carcinoma, one patient (of 8) with basal cell carcinoma of the nose, one patient (of 27) with carcinoma of the lung, and one patient (of 59) with nasopharyngeal carcinoma.

• Research Organization: Univ. of California, San Francisco
• OSTI ID: 7181919
• Journal Information: Cancer; (United States), Journal Name: Cancer; (United States) Vol. 38:1; ISSN CANCA
• Country of Publication: United States
• Language: English

Related Subjects

550601* -- Medicine-- Unsealed Radionuclides in Diagnostics
62 RADIOLOGY AND NUCLEAR MEDICINE
BETA DECAY RADIOISOTOPES
BLOOD SERUM
BODY
BONE TISSUES
CONNECTIVE TISSUE
DAYS LIVING RADIOISOTOPES
DISEASES
ELECTRON CAPTURE RADIOISOTOPES
FEMALE GENITALS
GLANDS
GONADS
HEPATOMAS
INTERMEDIATE MASS NUCLEI
IODINE 125
IODINE ISOTOPES
ISOTOPE APPLICATIONS
ISOTOPES
LUNGS
MALE GENITALS
MAMMARY GLANDS
NEOPLASMS
NUCLEI
ODD-EVEN NUCLEI
ORGANIC COMPOUNDS
ORGANS
OVARIES
PATIENTS
PROTEINS
RADIOASSAY
RADIOIMMUNOASSAY
RADIOISOTOPES
RESPIRATORY SYSTEM
TESTES
TISSUES
TRACER TECHNIQUES