Mutation assays involving blood cells that metabolize toxic substances
Patent
·
OSTI ID:7143477
A line of human blood cells which have high levels of oxidative activity (such as oxygenase, oxidase, peroxidase, and hydroxylase activity) is disclosed. Such cells grow in suspension culture, and are useful to determine the mutagenicity of xenobiotic substances that are metabolized into toxic or mutagenic substances. Mutation assays using these cells, and other cells with similar characteristics, are also disclosed. 2 figs.
- Assignee:
- Massachusetts Inst. of Tech., Cambridge, MA (United States)
- Patent Number(s):
- US 4532204; A
- Application Number:
- PPN: US 6-399851
- OSTI ID:
- 7143477
- Resource Relation:
- Patent File Date: 19 Jul 1982
- Country of Publication:
- United States
- Language:
- English
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