Modulation of gene expression by fission-spectrum neutrons
Conference
·
OSTI ID:7037547
Ionizing radiations can produce mutant inductions, neoplastic transformation, or cell death; alternatively, the cells can recover from the radiation insult. The molecular mechanisms involved in these processes are not well understood. These studies were designed to examine alterations in gene expression following low doses of neutron irradiation that might indicate the cellular mechanisms underscoring normal cell recovery or the onset of neoplastic transformation. We examined modulation of specific gene expression in Syrian Hamster Embryonic cells at intervals following exposure to fission-spectrum neutrons (24 cGy) from the JANUS reactor at Argonne. 9 refs.
- Research Organization:
- Argonne National Lab., IL (USA)
- DOE Contract Number:
- W-31109-ENG-38
- OSTI ID:
- 7037547
- Report Number(s):
- CONF-881134-1; ON: DE88012000
- Country of Publication:
- United States
- Language:
- English
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Related Subjects
560120* -- Radiation Effects on Biochemicals
Cells
& Tissue Culture
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ANIMAL CELLS
BARYONS
BIOLOGY
ELEMENTARY PARTICLES
EMBRYONIC CELLS
ENZYME INDUCTION
FERMIONS
FISSION NEUTRONS
GENE REGULATION
HADRONS
MESSENGER-RNA
NEUTRONS
NUCLEIC ACIDS
NUCLEONS
ORGANIC COMPOUNDS
RADIOBIOLOGY
RNA
Cells
& Tissue Culture
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ANIMAL CELLS
BARYONS
BIOLOGY
ELEMENTARY PARTICLES
EMBRYONIC CELLS
ENZYME INDUCTION
FERMIONS
FISSION NEUTRONS
GENE REGULATION
HADRONS
MESSENGER-RNA
NEUTRONS
NUCLEIC ACIDS
NUCLEONS
ORGANIC COMPOUNDS
RADIOBIOLOGY
RNA